Edetic Acid

Edetic Acid

SCHEMBL190043

O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[H+].[H+].[Na+].[Na+]

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE known ✓ P12821 1/20 0.48
CA4 known ✓ P22748 8/20 0.40
CA2 known ✓ P00918 4/20 0.35
CA1 known ✓ P00915 4/20 0.35
KDM4E B2RXH2 2/20 0.73
ALOX15 P16050 2/20 0.73
MAPT P10636 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
TDP1 Q9NUW8 2/20 0.48
EYA2 O00167 1/20 0.48
APP P05067 1/20 0.48
BLM P54132 2/20 0.46
PMP22 Q01453 2/20 0.46
LMNA P02545 1/20 0.46
CHRM2 P08172 1/20 0.46
ADRA2A P08913 1/20 0.46
TSHR P16473 1/20 0.46
DRD1 P21728 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL3374424 1.00 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL30259751 0.97 KDM4E (0.77) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL352497 0.97 KDM4E (0.70) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL3835316 0.97 KDM4E (0.76) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL42427 0.97 KDM4E (0.76) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL906 0.97 KDM4E (0.76) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL44287 0.97 KDM4E (0.76) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL5315227 0.97 KDM4E (0.68) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL243998 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL1090576 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276819-A1 IRON FORTIFIED TEA-BASED BEVERAGE GLOBAL LOAN AGENCY SERVICES GMBH (DE) 2023-09-07 US claimed
US-20160221233-A1 Method of forming a fibrous product TEKNOLOGIAN TUTKIMUSKESKUS VTT OY (FI) 2016-08-04 US claimed
EP-3044253-A1 METHOD OF FORMING A FIBROUS PRODUCT Teknologian tutkimuskeskus VTT Oy (FI) 2016-07-20 EP claimed
WO-2015036659-A1 METHOD OF FORMING A FIBROUS PRODUCT TEKNOLOGIAN TUTKIMUSKESKUS VTT (FI) 2015-03-19 WO claimed
EP-0777495-B1 STABLE, AQUEOUS ALFA INTERFERON SOLUTION FORMULATIONS SCHERING CORP (US) 2000-07-19 EP claimed
EP-0443007-B1 AN EXTERNAL ANALGESIC LOTION AND METHOD OF MAKING IVY JEFFERY W (US) 1995-03-08 EP claimed
EP-0443007-A4 AN EXTERNAL ANALGESIC LOTION AND METHOD OF MAKING 1993-03-03 EP claimed
US-5124320-A An external analgesic lotion containing active ingredients of camphor and menthol and method of making such lotion AU PHARMACEUTICALS, INC. 1992-06-23 US claimed
EP-0443007-A1 AN EXTERNAL ANALGESIC LOTION AND METHOD OF MAKING. IVY JEFFERY W (US) 1991-08-28 EP claimed
US-5043307-A Steaming, dealuminizing MOBIL OIL CORP. (US) 1991-08-27 US claimed
US-5013726-A External analgesic lotion containing active ingredients of methyl salicylate and camphor and menthol and method of making such lotion AU PHARMACEUTICALS, INC. 1991-05-07 US claimed
WO-1991004010-A1 AN EXTERNAL ANALGESIC LOTION AND METHOD OF MAKING IVY JEFFERY W (US) 1991-04-04 WO claimed
US-4876411-A DEALUMINIZATION MOBIL OIL CORPORATION (US) 1989-10-24 US claimed
US-4093560-A REMOVING ALUMINUM FROM ALUMINOSILICATES BY COMPLEXING WITH AN AMMONIUM OR ALKALI METAL SALT MOBIL OIL CORPORATION (US) 1978-06-06 US claimed
US-20260109872-A1 Ink Jet Ink Composition And Ink Jet Recording Method SEIKO EPSON CORP (JP) 2026-04-23 US disclosed
US-20260071089-A1 Ink Jet Composition Set SEIKO EPSON CORP (JP) 2026-03-12 US disclosed
EP-4285947-B1 METHOD FOR PRODUCING COATED MEDICAL DEVICE TORAY INDUSTRIES (JP) 2025-12-03 EP disclosed
US-4312947-A SERIAL PASSAGE IN CAT KIDNEY CELLS BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1982-01-26 US disclosed
US-4093560-A REMOVING ALUMINUM FROM ALUMINOSILICATES BY COMPLEXING WITH AN AMMONIUM OR ALKALI METAL SALT MOBIL OIL CORPORATION (US) 1978-06-06 US disclosed
US-4044158-A MEAT, WATER, SUGAR, VEGETABLE PROTEIN, ANTIMYCOTIC THE QUAKER OATS COMPANY (US) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109872-A1 Ink Jet Ink Composition And Ink Jet Recording Method COPE, EED, VCL ACE 3423/4885CA4 3356/4885CA2 4233/4885
US-20260071089-A1 Ink Jet Composition Set CA1, CA3, CA12 ACE 4577/4885CA4 11/4885CA2 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.