SCHEMBL1908844

SCHEMBL1908844

COc1cccc(C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
TSHR P16473 2/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
LMNA P02545 2/20 0.35
HIF1A Q16665 1/20 0.35
NR3C1 P04150 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
HSD17B10 Q99714 1/20 0.34
AGER Q15109 1/20 0.34
RPS6KA2 Q15349 1/20 0.34
TOP1 P11387 1/20 0.34
APAF1 O14727 1/20 0.34
MITF O75030 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28439942 0.92 HTR7 (0.40) HPGDSMN1; SMN2TSHRRAB9ANPC1
SCHEMBL20304 0.92 HTR7 (0.40) HPGDSMN1; SMN2TSHRRAB9ANPC1
SCHEMBL4216711 0.91 HTR7 (0.39) HPGDSMN1; SMN2TSHRRAB9ANPC1
SCHEMBL30181989 0.91 HTR7 (0.39) HPGDSMN1; SMN2TSHRRAB9ANPC1
SCHEMBL26657101 0.91 HTR7 (0.39) HPGDSMN1; SMN2TSHRRAB9ANPC1
SCHEMBL4444992 0.91 SMN1; SMN2 (0.38) HPGDSMN1; SMN2TSHRRAB9ANPC1
SCHEMBL30068977 0.91 HTR7 (0.39) HPGDSMN1; SMN2TSHRRAB9ANPC1
SCHEMBL5502813 0.91 HTR7 (0.39) HPGDSMN1; SMN2TSHRRAB9ANPC1
Hydrochloric Acid SCHEMBL29391428 0.91 HTR7 (0.39) HPGDSMN1; SMN2TSHRRAB9ANPC1
SCHEMBL3398502 0.90 HTR7 (0.40) HPGDSMN1; SMN2TSHRRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787827-B2 Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions DONGGUAN STEPHEN CATALYST CO., LTD. (CN) 2023-10-17 US disclosed
US-11793066-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-11765965-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11649258-B2 Complexes JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2023-05-16 US disclosed
US-10033004-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-24 US disclosed
US-20180198079-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-12 US disclosed
US-10008679-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-26 US disclosed
US-10001487-B2 Glucose derivative, and cell imaging method and imaging agent using said derivative HIROSAKI UNIVERSITY (JP) 2018-06-19 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-24 US disclosed
US-20110155955-A1 ELECTRON-TRANSPORTING MATERIALS BOE TECHNOLOGY GROUP CO., LTD. (CN) 2011-06-30 US disclosed
US-20110121235-A1 COMPOUND COMPRISING PHENYL PYRIDINE UNITS BOE TECHNOLOGY GROUP CO., LTD. (CN) 2011-05-26 US disclosed
US-20110108807-A1 POLYMER FOR OPTOELECTRONIC DEVICE GENERAL ELECTRIC COMPANY (US) 2011-05-12 US disclosed
US-20110082098-A1 NOVOBIOCIN ANALOGUES AND TREATMENT OF POLYCYSTIC KIDNEY DISEASE UNIVERSITY OF KANSAS (US) 2011-04-07 US disclosed
US-20110077373-A1 POLYMER AND OPTOELECTRONIC DEVICE COMPRISING THE SAME GENERAL ELECTRIC COMPANY (US) 2011-03-31 US disclosed
US-20110015059-A1 CYCLIC COMPOUND, ITS METAL COMPLEX AND MODIFIED METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-20 US disclosed
US-20100308313-A1 Organic Material Containing Oligophenylene Skeleton and Light-Emitting Device Using the Same NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY 2010-12-09 US disclosed
EP-2123638-A1 METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2009-11-25 EP disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 WO disclosed
WO-2009021126-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180198079-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP HPGD 1752/4885SMN1; SMN2 4637/4885TSHR 3995/4885
US-11765965-B2 Organic electroluminescent materials and devices YBX3, YBX1, LEF1 HPGD 4516/4885SMN1; SMN2 3721/4885TSHR 601/4885
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, ICMT HPGD 4079/4885SMN1; SMN2 1547/4885TSHR 4512/4885
US-11787827-B2 Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions WEE1, WEE2, NOTUM HPGD 2840/4885SMN1; SMN2 4873/4885TSHR 677/4885
US-10008679-B2 Organic electroluminescent materials and devices EPCAM, ICMT, ORAI2 HPGD 2630/4885SMN1; SMN2 3563/4885TSHR 4646/4885
US-20110121235-A1 COMPOUND COMPRISING PHENYL PYRIDINE UNITS CRY1, C1S, C3AR1 HPGD 1229/4885SMN1; SMN2 4456/4885TSHR 1585/4885
US-20100308313-A1 Organic Material Containing Oligophenylene Skeleton and Light-Emitting Device Using the Same BMP2, SOST, BMP4 HPGD 4397/4885SMN1; SMN2 3051/4885TSHR 4853/4885
US-10001487-B2 Glucose derivative, and cell imaging method and imaging agent using said derivative SLC2A4, SLC2A1, G6PD HPGD 641/4885SMN1; SMN2 4585/4885TSHR 4379/4885
US-20110155955-A1 ELECTRON-TRANSPORTING MATERIALS C3AR1, C1S, C1R HPGD 1018/4885SMN1; SMN2 4160/4885TSHR 2271/4885
US-11649258-B2 Complexes AP2M1, AP1M1, INF2 HPGD 3629/4885SMN1; SMN2 1895/4885TSHR 4166/4885
US-20110015059-A1 CYCLIC COMPOUND, ITS METAL COMPLEX AND MODIFIED METAL COMPLEX NR4A1, NR4A2, NR3C2 HPGD 3861/4885SMN1; SMN2 2077/4885TSHR 1011/4885
US-11793066-B2 Organic electroluminescent materials and devices EPCAM, ICMT, ORAI2 HPGD 2630/4885SMN1; SMN2 3563/4885TSHR 4646/4885
US-20110082098-A1 NOVOBIOCIN ANALOGUES AND TREATMENT OF POLYCYSTIC KIDNEY DISEASE PKD1, PKD2, HSP90B1 HPGD 1357/4885SMN1; SMN2 4743/4885TSHR 4176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.