Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.34 |
| ▸ | UGCG | Q16739 | 11/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856929 | 0.84 | CCR2 (0.35) | CCR2F10 | |
| SCHEMBL19856992 | 0.82 | CCR2 (0.34) | CCR2ALDH1A1P2RX7 | |
| SCHEMBL19856933 | 0.80 | HPGD (0.36) | CCR2ALDH1A1 | |
| SCHEMBL19856960 | 0.80 | PLA2G10 (0.38) | CCR2F10 | |
| SCHEMBL19856928 | 0.79 | CCR1 (0.35) | F10 | |
| SCHEMBL19856988 | 0.78 | NOD2 (0.41) | ALDH1A1 | |
| SCHEMBL19856957 | 0.78 | AVPR1A (0.34) | CCR2 | |
| SCHEMBL19856975 | 0.77 | SMN1; SMN2 (0.34) | CCR2ALDH1A1F10 | |
| SCHEMBL19856993 | 0.77 | PLA2G10 (0.38) | CCR2 | |
| SCHEMBL19857030 | 0.77 | PLA2G10 (0.38) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |