Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856935 | 0.93 | PARP10 (0.40) | BTKKCNH2CYP2C8PARP10PARP14 | |
| SCHEMBL19856981 | 0.92 | SIRT3 (0.38) | MEN1KMT2ANOD2NOD1 | |
| SCHEMBL19856960 | 0.92 | PLA2G10 (0.38) | KCNH2NOD2NOD1MCL1PLA2G10 | |
| SCHEMBL19856991 | 0.91 | SLC6A7 (0.37) | NOD2NOD1PLA2G10 | |
| SCHEMBL19856988 | 0.90 | NOD2 (0.41) | MEN1KMT2AHTTNOD2NOD1 | |
| SCHEMBL19856969 | 0.89 | BTK (0.37) | BTKKCNH2CYP2C8CHEK2PARP10 | |
| SCHEMBL19857001 | 0.86 | TRPA1 (0.40) | MEN1KMT2ANOD2NOD1 | |
| SCHEMBL19856992 | 0.82 | CCR2 (0.34) | MEN1KMT2APLA2G10 | |
| SCHEMBL19856952 | 0.81 | ALDH1A1 (0.39) | NOD2NOD1MCL1 | |
| SCHEMBL19856929 | 0.80 | CCR2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |