SCHEMBL19984182

SCHEMBL19984182

CNCc1cn(Sc2cccc(OC(F)(F)F)c2)c2cc(Nc3ccc(C)c(F)c3F)ccc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19984025 0.91 MAPK14 (0.32)
SCHEMBL19984154 0.86 P2RX7 (0.34) P2RX7
SCHEMBL19983777 0.86 ADRB2 (0.37) P2RX7
SCHEMBL19983775 0.86 EGFR (0.34) P2RX7
SCHEMBL19983885 0.84 FBP1 (0.39) P2RX7
SCHEMBL16626757 0.81 FBP1 (0.37) P2RX7
SCHEMBL19983791 0.80 KDR (0.33) P2RX7
Hydrochloric Acid SCHEMBL16618983 0.80 FBP1 (0.37) P2RX7
SCHEMBL19984027 0.79 MAPK14 (0.37)
SCHEMBL19984007 0.79 MAT2A (0.34) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052484-B1 SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME DAE WOONG PHARMA (KR) 2018-03-21 EP disclosed