Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984271 | 0.91 | HTR2A (0.34) | HTR2ASLC6A4KCNH2SMN1; SMN2GAA | |
| SCHEMBL19984154 | 0.84 | P2RX7 (0.34) | ALDH1A1 | |
| SCHEMBL16626516 | 0.82 | RORC (0.43) | — | |
| Hydrochloric Acid SCHEMBL16618865 | 0.81 | RORC (0.43) | — | |
| SCHEMBL19983907 | 0.81 | FPR1 (0.36) | HTR2ASLC6A4KCNH2SMN1; SMN2ALDH1A1 | |
| SCHEMBL19983937 | 0.79 | MPO (0.37) | HTR2ASLC6A4KCNH2ALDH1A1P2RX3 | |
| SCHEMBL19984021 | 0.79 | GAK (0.40) | HTR2ASLC6A4KCNH2ALDH1A1 | |
| SCHEMBL19983775 | 0.79 | EGFR (0.34) | — | |
| SCHEMBL19984163 | 0.78 | FADS1 (0.36) | HTR2ASLC6A4KCNH2ALDH1A1P2RX3 | |
| SCHEMBL19983885 | 0.78 | FBP1 (0.39) | HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |