Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254055 | 0.76 | DAO (0.35) | DAOGABRA1GABRB2GRM5HTR2A | |
| SCHEMBL16167311 | 0.73 | DAO (0.36) | DAOGABRA1GABRB2GRM5HTR2A | |
| Hydrochloric Acid SCHEMBL929583 | 0.72 | DAO (0.35) | DAOGABRA1GABRB2GRM5HTR2A | |
| SCHEMBL2014395 | 0.69 | DRD2 (0.39) | DAOHTR2AHTR2CHTR2B | |
| SCHEMBL29488434 | 0.69 | ADRA2B (0.44) | DAOGABRA1GABRB2 | |
| SCHEMBL142479 | 0.69 | ADRA2B (0.44) | DAOGABRA1GABRB2 | |
| SCHEMBL1155762 | 0.69 | CYP2A6 (0.38) | — | |
| SCHEMBL3772536 | 0.68 | MGLL (0.53) | DAO | |
| SCHEMBL1452942 | 0.67 | ALDH1A1 (0.41) | DAOGABRA1GABRB2GRM5 | |
| SCHEMBL9839840 | 0.66 | ADRA2B (0.43) | DAOGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088346-B2 | Alkene hydrofunctionalization reactions | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-01-03 | — | — | US | claimed |
| US-20090069580-A1 | Alkene Hydrofunctionalization Reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-12 | — | — | US | claimed |
| US-9357772-B2 | Antimicrobial cationic polycarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-06-07 | — | — | US | disclosed |
| EP-2983692-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | International Business Machines Corporation (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2983679-A2 | ANTIMICROBIAL CATIONIC POLYCARBONATES | International Business Machines Corporation (US) | 2016-02-17 | — | — | EP | disclosed |
| US-8962772-B2 | Antimicrobial surface modified silicone rubber and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-02-24 | — | — | US | disclosed |
| US-20150005457-A1 | ANTIMICROBIAL SURFACE MODIFIED SILICONE RUBBER AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2015-01-01 | — | — | US | disclosed |
| WO-2014168762-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014168771-A2 | ANTIMICROBIAL CATIONIC POLYCARBONATES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-10-16 | — | — | WO | disclosed |
| US-20140301968-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-09 | — | — | US | disclosed |
| US-8088346-B2 | Alkene hydrofunctionalization reactions | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090069580-A1 | Alkene Hydrofunctionalization Reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069580-A1 | Alkene Hydrofunctionalization Reactions | ADH1A, ADH1C, ADH5 | DAO 274/4885GABRA1 2634/4885GABRB2 1628/4885 |
| US-20140301968-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | VDR, GC, CYP24A1 | DAO 2336/4885GABRA1 3679/4885GABRB2 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.