Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199876 | 0.76 | DAO (0.37) | DAOHTR2CHTR2BHTR2AGRM5 | |
| SCHEMBL2014395 | 0.74 | DRD2 (0.39) | DAOHTR2CHTR2BHTR2ALIPG | |
| SCHEMBL16167311 | 0.71 | DAO (0.36) | DAOHTR2CHTR2BHTR2AADRA2A | |
| Hydrochloric Acid SCHEMBL929583 | 0.69 | DAO (0.35) | DAOHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL623217 | 0.69 | ALDH1A1 (0.38) | HTR2CHTR2BKMT2A | |
| SCHEMBL151785 | 0.68 | HTR2A (0.32) | DAOHTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL25720743 | 0.66 | HTR2C (0.44) | HTR2CHTR2BHTR2AADRA2CHTR1A | |
| SCHEMBL29488434 | 0.66 | ADRA2B (0.44) | DAOLIPGADRA2AADRA2BADRA2C | |
| SCHEMBL142479 | 0.66 | ADRA2B (0.44) | DAOLIPGADRA2AADRA2BADRA2C | |
| SCHEMBL3772536 | 0.65 | MGLL (0.53) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088346-B2 | Alkene hydrofunctionalization reactions | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-01-03 | — | — | US | claimed |
| US-20110124755-A1 | Polyisocyanurates | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-05-26 | — | — | US | claimed |
| US-20090069580-A1 | Alkene Hydrofunctionalization Reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-12 | — | — | US | claimed |
| US-9974303-B2 | Cationic polymers for antimicrobial applications and delivery of bioactive materials | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-05-22 | — | — | US | disclosed |
| US-9717797-B2 | Polycarbonates bearing aromatic N-heterocycles for drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-08-01 | — | — | US | disclosed |
| US-9357772-B2 | Antimicrobial cationic polycarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-06-07 | — | — | US | disclosed |
| EP-2983692-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | International Business Machines Corporation (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2983679-A2 | ANTIMICROBIAL CATIONIC POLYCARBONATES | International Business Machines Corporation (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2984117-A1 | VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS | International Business Machines Corporation (US) | 2016-02-17 | — | — | EP | disclosed |
| US-20150157723-A1 | POLYCARBONATES BEARING AROMATIC N-HETEROCYCLES FOR DRUG DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-06-11 | — | — | US | disclosed |
| US-8962772-B2 | Antimicrobial surface modified silicone rubber and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-02-24 | — | — | US | disclosed |
| US-8088346-B2 | Alkene hydrofunctionalization reactions | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110269917-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | CENTRAL GLASS CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| US-20110243848-A1 | STAR POLYMERS, METHODS OF PREPARATION THEREOF, AND USES THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2011078804-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011078803-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110151566-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110152167-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20090069580-A1 | Alkene Hydrofunctionalization Reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110243848-A1 | STAR POLYMERS, METHODS OF PREPARATION THEREOF, AND USES THEREOF | AS3MT, STARD7, MCM5 | DAO 4773/4885HTR2C 4719/4885HTR2B 4649/4885 |
| US-20150157723-A1 | POLYCARBONATES BEARING AROMATIC N-HETEROCYCLES FOR DRUG DELIVERY | PAH, SULT1E1, SULT1A1 | DAO 1540/4885HTR2C 343/4885HTR2B 84/4885 |
| US-20090069580-A1 | Alkene Hydrofunctionalization Reactions | ADH1A, ADH1C, ADH5 | DAO 274/4885HTR2C 1760/4885HTR2B 1854/4885 |
| US-20110124755-A1 | Polyisocyanurates | SLC16A3, SLC16A8, METTL3 | DAO 334/4885HTR2C 2175/4885HTR2B 1976/4885 |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | MLEC, NOD2, PAM | DAO 1054/4885HTR2C 3382/4885HTR2B 2137/4885 |
| US-20110269917-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | NOTUM, PFAS, PCNA | DAO 2011/4885HTR2C 4019/4885HTR2B 4176/4885 |
| US-20110152167-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | SAMM50, ADRM1, UFM1 | DAO 110/4885HTR2C 4494/4885HTR2B 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.