Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002683 | 0.86 | KMT2A (0.39) | RORCKMT2AMTNR1BPIK3CDFPR1 | |
| SCHEMBL20002736 | 0.76 | RORC (0.36) | RORCKMT2A | |
| SCHEMBL20003061 | 0.76 | RORC (0.54) | RORC | |
| SCHEMBL20003010 | 0.75 | RORC (0.43) | RORCMTNR1BFPR1FPR2ALDH1A1 | |
| SCHEMBL20002255 | 0.74 | CCR5 (0.49) | RORCKMT2A | |
| SCHEMBL20002972 | 0.74 | L3MBTL1 (0.41) | RORCKMT2AMAPTNOTUMGRIN2B | |
| SCHEMBL20002719 | 0.73 | HSD11B1 (0.48) | KMT2AALDH1A1 | |
| SCHEMBL20003196 | 0.73 | HSD11B1 (0.48) | KMT2AALDH1A1 | |
| SCHEMBL20002297 | 0.72 | NOTUM (0.47) | RORCKMT2AMAPTNOTUMGRIN2B | |
| SCHEMBL20003024 | 0.70 | NOTUM (0.44) | KMT2AMAPTKDM4EALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |