Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042685 | 0.88 | HTT (0.42) | P2RX7GBA1ABL1BCRCYP1A2 | |
| SCHEMBL20042652 | 0.88 | P2RX7 (0.66) | P2RX7MEN1KMT2AHPGDABL1 | |
| SCHEMBL20042817 | 0.88 | PKM (0.44) | P2RX7MEN1KMT2AHPGDGBA1 | |
| SCHEMBL20042705 | 0.86 | EPHX2 (0.45) | P2RX7EPHX2 | |
| SCHEMBL20042760 | 0.85 | P2RX7 (0.45) | P2RX7MEN1KMT2AGBA1ABL1 | |
| SCHEMBL20042751 | 0.85 | HSD17B10 (0.49) | P2RX7MEN1KMT2AHPGDGBA1 | |
| SCHEMBL20042839 | 0.85 | P2RX7 (0.45) | P2RX7MEN1KMT2AHPGDTSHR | |
| SCHEMBL20042702 | 0.85 | P2RX7 (0.49) | P2RX7MEN1KMT2ATSHRCYP1A2 | |
| SCHEMBL20043089 | 0.84 | P2RX7 (0.52) | P2RX7ABL1BCRSLC6A7SMN1; SMN2 | |
| SCHEMBL20042728 | 0.83 | MEN1 (0.42) | MEN1KMT2AGBA1EPHX2SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |