SCHEMBL20165756

SCHEMBL20165756

COc1c(C(C)(C)C)cc2c(c1-c1cc(C)cc(C)c1)C=C(C)C2[Si](C)(C)Cl

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29992354 1.00 PTGS2 (0.30) PTGS2PTGS1
SCHEMBL20165779 0.91 PTGS2 (0.32) PTGS2PTGS1
SCHEMBL29874052 0.91 PTGS2 (0.32) PTGS2PTGS1
SCHEMBL14645995 0.90 PTGS2 (0.30) PTGS2PTGS1
SCHEMBL14645960 0.87 PDE4B (0.34)
SCHEMBL31355509 0.87
SCHEMBL31342807 0.87
SCHEMBL14645946 0.86 TDO2 (0.32)
SCHEMBL25865225 0.86
SCHEMBL25951024 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682201-A1 BETA-NUCLEATED MULTIMODAL COPOLYMERS Borealis GmbH (AT) 2026-01-21 EP disclosed
EP-3820939-B1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH IMPROVED BALANCE OF PROPERTIES BOREALIS AG (AT) 2024-06-05 EP disclosed
US-11981801-B2 Polypropylene composition BOREALIS AG (AT) 2024-05-14 US disclosed
US-11807655-B2 Catalysts BOREALIS AG (AT) 2023-11-07 US disclosed
US-11807655-B2 Catalysts BOREALIS AG (AT) 2023-11-07 US disclosed
CN-113474406-B Nucleated propylene polymer compositions with high toughness 博里利斯股份公司 2023-09-15 CN disclosed
US-20230242748-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-08-03 US disclosed
CN-112424241-B Catalyst 博里利斯股份公司 2023-06-06 CN disclosed
US-11643427-B2 Catalysts BOREALIS AG (AT) 2023-05-09 US disclosed
CN-112334532-B Heterophasic polypropylene composition with improved balance of properties 博里利斯股份公司 2023-03-31 CN disclosed
CN-110741039-A Polypropylene composition 博里利斯股份公司 2020-01-31 CN disclosed
WO-2020011825-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH IMPROVED BALANCE OF PROPERTIES BOREALIS AG (AT) 2020-01-16 WO disclosed
EP-3567060-A1 PROCESS FOR PREPARING HETEROPHASIC PROPYLENE COPOLYMERS Borealis AG (AT) 2019-11-13 EP disclosed
EP-3562831-A1 CATALYSTS Borealis AG (AT) 2019-11-06 EP disclosed
US-20190308995-A1 CATALYSTS BOREALIS AG (AT) 2019-10-10 US disclosed
EP-3541823-A1 CATALYSTS Borealis AG (AT) 2019-09-25 EP disclosed
EP-3456776-A1 POLYPROPYLENE COMPOSITION Borealis AG (AT) 2019-03-20 EP disclosed
WO-2019012110-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2019-01-17 WO disclosed
WO-2018122134-A1 CATALYSTS BOREALIS AG (AT) 2018-07-05 WO disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190308995-A1 CATALYSTS SIGMAR1, H1-2, CBR1 PTGS2 3756/4885PTGS1 3935/4885
US-11807655-B2 Catalysts SOD1, MT-CO2, MT-CO1 PTGS2 2491/4885PTGS1 3181/4885
US-11643427-B2 Catalysts MLX, HAX1, CHRM1 PTGS2 3439/4885PTGS1 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.