SCHEMBL202114

SCHEMBL202114

Oc1c(Sc2ccccc2)cccc1Sc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.50
MAPT P10636 3/20 0.48
KDM4E B2RXH2 1/20 0.48
NSD2 O96028 1/20 0.48
MAPK1 P28482 1/20 0.48
HPGD P15428 3/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CHRNA7 P36544 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 2/20 0.42
KMT2A Q03164 2/20 0.42
DHFR P00374 1/20 0.42
MEN1 O00255 1/20 0.42
BLM P54132 1/20 0.42
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL595125 0.89 ALDH1A1 (0.46) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL22647159 0.82 KDM4E (0.47) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL8720648 0.81 SIRT1 (0.42) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL15509355 0.81 SIRT1 (0.42) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL795029 0.81 SIRT1 (0.54) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL487237 0.80 SIRT1 (0.50) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL3900082 0.78 SIRT1 (0.52) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL3897205 0.78 SIRT1 (0.52) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL3897215 0.78 SIRT1 (0.52) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL15509370 0.78 STAT3 (0.44) SIRT1MAPTKDM4ENSD2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3019510-B1 USE OF IMMOBILIZED MOLYBDEN- UND TUNGSTEN-CONTAINING CATALYSTS IN OLEFIN CROSS METATHESIS VERBIO VER BIOENERGIE AG (DE) 2020-12-02 EP disclosed
EP-3662996-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS Verbio Vereinigte BioEnergie AG (DE) 2020-06-10 EP disclosed
US-10343153-B2 Metathesis catalysts and reactions using the catalysts XIMO AG (CH) 2019-07-09 US disclosed
US-10230023-B2 Color converter BASF SE (DE) 2019-03-12 US disclosed
EP-3019511-B1 IMMOBILIZED METATHESIS TUNGSTEN CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS XIMO AG (CH) 2019-01-02 EP disclosed
US-10071950-B2 Use of immobilized molybdenum- and tungsten-containing catalysts in olefin cross metathesis XIMO AG (CH) 2018-09-11 US disclosed
US-9919299-B2 Metathesis catalysts and reactions using the catalysts XIMO AG (CH) 2018-03-20 US disclosed
EP-2718395-B1 Novel illumination device comprising a colour converter BASF SE (DE) 2018-02-28 EP disclosed
US-20160284947-A1 NOVEL COLOR CONVERTER BASF SE (DE) 2016-09-29 US disclosed
US-9406848-B2 Color converter BASF SE (DE) 2016-08-02 US disclosed
EP-2029573-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2009-03-04 EP disclosed
US-20080287678-A1 Multiple Chromophores Based on Rylene BASF AKTIENGESELLSCHAFT (DE) 2008-11-20 US disclosed
US-20080245411-A1 Fluorescent Solar Conversion Cells Based on Fluorescent Terylene Dyes BASF SE 2008-10-09 US disclosed
EP-1927141-A2 FLUORESCENT SOLAR CONVERSION CELLS BASED ON FLUORESCENT TERYLENE DYES BASF SE (DE) 2008-06-04 EP disclosed
EP-1917311-A2 MULTIPLE CHROMOPHORES BASF SE (DE) 2008-05-07 EP disclosed
EP-1904497-A1 SUBSTITUTED RYLENE DERIVATIVES BASF SE (DE) 2008-04-02 EP disclosed
WO-2007138051-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2007-12-06 WO disclosed
WO-2007031446-A2 FLUORESCENT SOLAR CONVERSION CELLS BASED ON FLUORESCENT TERYLENE DYES BASF SE (DE) 2007-03-22 WO disclosed
WO-2007014902-A2 MULTIPLE CHROMOPHORES BASED ON RYLENE BASF SE (DE) 2007-02-08 WO disclosed
WO-2007006717-A1 SUBSTITUTED RYLENE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10343153-B2 Metathesis catalysts and reactions using the catalysts MSMO1, SQLE, MOGAT2 SIRT1 3164/4885MAPT 3427/4885KDM4E 3415/4885
US-20080287678-A1 Multiple Chromophores Based on Rylene TDO2, PPOX, NPY1R SIRT1 910/4885MAPT 4684/4885KDM4E 706/4885
US-10071950-B2 Use of immobilized molybdenum- and tungsten-containing catalysts in olefin cross metathesis DUOX1, DUOX2, MSN SIRT1 2939/4885MAPT 3914/4885KDM4E 3943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.