Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HBB | P68871 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30013278 | 1.00 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1MAPTMAPK1HBB | |
| SCHEMBL20486800 | 0.83 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1MAPTMAPK1HBB | |
| SCHEMBL28338514 | 0.82 | SIGMAR1 (0.44) | SIGMAR1ALDH1A1MAPTMAPK1HBB | |
| SCHEMBL20487160 | 0.78 | MAPT (0.54) | SIGMAR1MAPTTDP1MEN1KMT2A | |
| SCHEMBL29411056 | 0.74 | ALDH1A1 (0.57) | SIGMAR1ALDH1A1MAPTMAPK1HBB | |
| SCHEMBL19974241 | 0.74 | ALDH1A1 (0.57) | SIGMAR1ALDH1A1MAPTMAPK1HBB | |
| SCHEMBL30884614 | 0.71 | KDM4E (0.54) | SIGMAR1ALDH1A1MAPTMAPK1HBB | |
| SCHEMBL29208327 | 0.71 | KDM4E (0.54) | SIGMAR1ALDH1A1MAPTMAPK1HBB | |
| SCHEMBL29411029 | 0.70 | KDM4E (0.61) | SIGMAR1ALDH1A1MAPTMAPK1HBB | |
| SCHEMBL28326868 | 0.70 | KDM4E (0.61) | SIGMAR1ALDH1A1MAPTMAPK1HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573240-B | Selectively permeable graphene oxide membranes | 日东电工株式会社 | 2022-11-22 | — | — | CN | disclosed |
| EP-3589390-B1 | SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE | NITTO DENKO CORP (JP) | 2022-08-17 | — | — | EP | disclosed |
| US-20200261861-A1 | SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE | NITTO DENKO CORPORATION (JP) | 2020-08-20 | — | — | US | disclosed |
| CN-110573240-A | selectively permeable graphene oxide membranes | 日东电工株式会社 | 2019-12-13 | — | — | CN | disclosed |
| WO-2018160871-A2 | SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE | NITTO DENKO CORPORATION (JP) | 2018-09-07 | — | — | WO | disclosed |