Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737631 | 0.90 | MAPT (0.52) | DRD2DRD4GAAALDH1A1MAPT | |
| SCHEMBL10272904 | 0.87 | SMN1; SMN2 (0.46) | DRD2DRD4MAPTLMNASMN1; SMN2 | |
| SCHEMBL10100725 | 0.82 | DRD2 (0.53) | DRD2DRD4GAAALDH1A1MAPT | |
| SCHEMBL24201682 | 0.79 | DRD2 (0.50) | DRD2DRD4GAAALDH1A1MAPT | |
| SCHEMBL12673265 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1LMNASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL12064448 | 0.78 | KIF11 (0.52) | MAPTLMNASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL13267322 | 0.75 | ASIC3 (0.49) | DRD2 | |
| SCHEMBL4991137 | 0.75 | PARP10 (0.56) | DRD2DRD4GAAS1PR1PARP1 | |
| SCHEMBL19251116 | 0.75 | PARP10 (0.64) | LMNAKDM4ESMN1; SMN2NPC1MAPK1 | |
| SCHEMBL23034499 | 0.74 | DRD2 (0.36) | DRD2DRD4GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025849-A1 | INHIBITORS OF NO PRODUCTION | CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2024-01-25 | — | — | US | disclosed |
| US-20210284601-A1 | ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2021-09-16 | — | — | US | disclosed |
| US-10208011-B2 | Benzothiophene estrogen receptor modulators | G1 THERAPEUTICS, INC. (US) | 2019-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208011-B2 | Benzothiophene estrogen receptor modulators | ESR1, GPER1, ESR2 | DRD2 2982/4885DRD4 3224/4885GAA 2956/4885 |
| US-20240025849-A1 | INHIBITORS OF NO PRODUCTION | NOS2, NOS1, NOS3 | DRD2 3350/4885DRD4 3295/4885GAA 799/4885 |
| US-20210284601-A1 | ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS | HAO2, AHR, HMOX1 | DRD2 703/4885DRD4 607/4885GAA 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.