SCHEMBL20809136

SCHEMBL20809136

FC(F)(F)CCc1cccc2nc(-c3ccccc3)ccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NQO2 P16083 1/20 0.40
TLR8 Q9NR97 2/20 0.39
TLR7 Q9NYK1 2/20 0.39
TDO2 P48775 1/20 0.38
ACHE P22303 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
CYP2C9 P11712 2/20 0.37
P2RX7 Q99572 1/20 0.36
NPC1 O15118 2/20 0.36
AR P10275 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809137 0.86 KMT2A (0.40) RAB9AMEN1KMT2AACHENPC1
SCHEMBL17666818 0.85 CDK9 (0.35) RAB9AMEN1KMT2ATLR8TLR7
SCHEMBL20809331 0.83 ACHE (0.50) TLR8TLR7ACHEABCG2CYP2C9
SCHEMBL20809040 0.77 TDO2 (0.40) RAB9AMEN1KMT2ANQO2TDO2
SCHEMBL26613601 0.76 CYP2C9 (0.48) RAB9AMEN1KMT2ANQO2TDO2
SCHEMBL20809328 0.75 KMT2A (0.47) RAB9AMEN1KMT2AACHENPC1
SCHEMBL20809327 0.75 TDO2 (0.43) RAB9AMEN1KMT2ANQO2TDO2
SCHEMBL20809323 0.75 RAB9A (0.38) RAB9AMEN1KMT2AACHECYP2C9
SCHEMBL20809138 0.74 MAOA (0.42) RAB9AMEN1KMT2ACYP2C9NPC1
SCHEMBL5255388 0.73 CYP1A2 (0.48) NQO2CYP2C9CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 RAB9A 4437/4885MEN1 4264/4885KMT2A 3312/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 RAB9A 4437/4885MEN1 4264/4885KMT2A 3312/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 RAB9A 3706/4885MEN1 3319/4885KMT2A 1849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.