SCHEMBL20809331

SCHEMBL20809331

FC(F)(F)CCc1cc(-c2ccccc2)nc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.46
PDE10A Q9Y233 1/20 0.46
HPGD P15428 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.45
SLC2A1 P11166 1/20 0.44
DHODH Q02127 1/20 0.44
CYP2C9 P11712 1/20 0.43
TLR8 Q9NR97 1/20 0.43
TLR7 Q9NYK1 1/20 0.43
TACR3 P29371 2/20 0.42
ACACA Q13085 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ACP1 P24666 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809328 0.88 KMT2A (0.47) ACHELMNASMN1; SMN2KDM4EHPGD
SCHEMBL20809330 0.87 LMNA (0.40) ACHELMNASMN1; SMN2KDM4EPDE10A
SCHEMBL20809136 0.83 RAB9A (0.40) ACHELMNASMN1; SMN2KDM4EPDE10A
SCHEMBL27914382 0.78 ACHE (0.58) ACHELMNASMN1; SMN2KDM4EPDE10A
Bromide SCHEMBL4455959 0.78 ACHE (0.53) ACHELMNASMN1; SMN2KDM4EPDE10A
SCHEMBL19258286 0.77 ACP1 (0.38) ACHELMNASMN1; SMN2KDM4EHPGD
SCHEMBL1259674 0.76 ACHE (0.59) ACHELMNASMN1; SMN2KDM4EPDE10A
SCHEMBL27917367 0.76 DHODH (0.58) ACHELMNASMN1; SMN2HPGDSLC2A1
SCHEMBL27367367 0.76 ACHE (0.51) ACHELMNASMN1; SMN2KDM4EPDE10A
SCHEMBL20809420 0.76 LMNA (0.48) ACHELMNASMN1; SMN2KDM4EPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 ACHE 37/4885LMNA 2627/4885SMN1; SMN2 4191/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 ACHE 37/4885LMNA 2627/4885SMN1; SMN2 4191/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 ACHE 6/4885LMNA 3274/4885SMN1; SMN2 3133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.