Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | BCL9 | O00512 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27566370 | 0.93 | GAA (0.54) | GAAKMT2APKMBCL9CTNNB1 | |
| Ethylene Glycol SCHEMBL28213517 | 0.93 | BCL9 (0.55) | GAAKMT2APKMBCL9CTNNB1 | |
| Butane SCHEMBL19439097 | 0.91 | BCL9 (0.67) | GAAKMT2APKMBCL9CTNNB1 | |
| Allylamine SCHEMBL1172613 | 0.87 | BCL9 (0.50) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL2616823 | 0.87 | GAA (0.56) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL2748042 | 0.86 | GAA (0.62) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL26374 | 0.83 | GAA (0.65) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL7063519 | 0.83 | GAA (0.65) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL25187205 | 0.83 | HTR2A (0.70) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL1532183 | 0.82 | GAA (0.54) | GAAKMT2APKMBCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11883500-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | MERCK SHARP & DOHME LLC (US) | 2024-01-30 | — | — | US | claimed |
| EP-3407916-B1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2023-12-20 | — | — | EP | claimed |
| US-20230147502-A1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILIATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2023-05-11 | — | — | US | claimed |
| US-20230099074-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | MERCK SHARP & DOHME LLC (US) | 2023-03-30 | — | — | US | claimed |
| US-11554172-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | MERCK SHARP & DOHME LLC (US) | 2023-01-17 | — | — | US | claimed |
| US-20210015930-A1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2021-01-21 | — | — | US | claimed |
| US-10869929-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | MERCK SHARP & DOHME CORP. (US) | 2020-12-22 | — | — | US | claimed |
| US-20200164085-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | MERCK SHARP & DOHME LLC | 2020-05-28 | — | — | US | claimed |
| US-20190030171-A1 | PHOSPONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-01-31 | — | — | US | claimed |
| EP-3407916-A2 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | Merck Sharp & Dohme Corp. (US) | 2018-12-05 | — | — | EP | claimed |
| US-6815562-B2 | REACTION OF NITROHALOGENS WITH ANILINES, A BASE AND A CATALYST, HYDROGENATION, | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-09 | — | — | US | claimed |
| CN-1517332-A | Method for prudicing amino-diphenylamine | — | 2004-08-04 | — | — | CN | claimed |
| CN-1517333-A | Method for preparing nitrodiphenylamine | — | 2004-08-04 | — | — | CN | claimed |
| US-20040143138-A1 | Process for the preparation of nitrodiphenylamines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | US | claimed |
| US-20040143139-A1 | Process for the production of aminodiphenylamines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | US | claimed |
| EP-0755394-A1 | A METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0687675-A2 | Irreversible HIV protease inhibitors, intermediates, compositions and processes for the preparation thereof | LG Chemical Limited (KR) | 1995-12-20 | — | — | EP | claimed |
| WO-1995028399-A1 | A METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | claimed |
| US-5059002-A | N-nitrophenyl carbamyl compounds | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-10-22 | — | — | US | claimed |
| EP-0434379-A1 | Second harmonic generation with archiral, straight-chain carbamic acid derivatives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200164085-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | CD44, FCGR2A, TNF | GAA 211/4885KMT2A 4262/4885PKM 3114/4885 |
| US-20230147502-A1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILIATE CELLULAR RETENTION OF COMPOUNDS | PHOSPHO1, SLC46A1, SLC19A1 | GAA 740/4885KMT2A 3452/4885PKM 427/4885 |
| US-20040143139-A1 | Process for the production of aminodiphenylamines | NUDT1, ITPA, NAAA | GAA 1910/4885KMT2A 286/4885PKM 1263/4885 |
| US-11883500-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | PHOSPHO1, TK1, MSN | GAA 1061/4885KMT2A 3481/4885PKM 408/4885 |
| US-20040143138-A1 | Process for the preparation of nitrodiphenylamines | HNMT, PNMT, NNMT | GAA 2182/4885KMT2A 514/4885PKM 1018/4885 |
| US-20230099074-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | CD44, FCGR2A, TNF | GAA 211/4885KMT2A 4262/4885PKM 3114/4885 |
| US-20190030171-A1 | PHOSPONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | PHOSPHO1, PHPT1, PSPH | GAA 638/4885KMT2A 4092/4885PKM 466/4885 |
| US-20210015930-A1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | PHOSPHO1, TK1, MSN | GAA 1061/4885KMT2A 3481/4885PKM 408/4885 |
| US-10869929-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | PHOSPHO1, TK1, MSN | GAA 1061/4885KMT2A 3481/4885PKM 408/4885 |
| US-11554172-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | PHOSPHO1, TK1, MSN | GAA 1061/4885KMT2A 3481/4885PKM 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.