Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL6673995 | 0.99 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTTHRBADRB2 | |
| SCHEMBL5755350 | 0.90 | POLB (0.41) | ALDH1A1GAAMAPTTHRBADRB2 | |
| Ether SCHEMBL4296253 | 0.86 | MAPT (0.41) | ALDH1A1GAAMAPTTHRBADRB2 | |
| Ether SCHEMBL6263790 | 0.85 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTTHRBADRB2 | |
| Ether SCHEMBL1678479 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTTHRBADRB2 | |
| Ether SCHEMBL1074739 | 0.82 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTTHRBADRB2 | |
| Ether SCHEMBL11031377 | 0.82 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTTHRBADRB2 | |
| Ether SCHEMBL9336351 | 0.81 | MAPT (0.39) | ALDH1A1GAAMAPTTHRBADRB2 | |
| Ether SCHEMBL3235371 | 0.79 | THRA (0.48) | THRBKCNH2TSHR | |
| Ether SCHEMBL7133434 | 0.78 | ADRB2 (0.41) | ALDH1A1GAAMAPTTHRBADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023145360-A1 | SURFACE PROTECTIVE SHEET AND TREATMENT METHOD | 日東電工株式会社 | 2023-08-03 | — | — | WO | disclosed |
| WO-2022201857-A1 | SURFACE PROTECTIVE SHEET AND TREATMENT METHOD | 日東電工株式会社 | 2022-09-29 | — | — | WO | disclosed |
| WO-2020137955-A1 | ADHESIVE SHEET | 日東電工株式会社 | 2020-07-02 | — | — | WO | disclosed |
| WO-2020137956-A1 | PROTECTIVE SHEET | 日東電工株式会社 | 2020-07-02 | — | — | WO | disclosed |
| WO-2020137953-A1 | METHOD FOR PREPARING ADHESIVE AGENT COMPOSITION, METHOD FOR MANUFACTURING PROTECTIVE SHEET, AND METHOD FOR MANUFACTURING GLASS UNIT | 日東電工株式会社 | 2020-07-02 | — | — | WO | disclosed |
| WO-2020137954-A1 | PROTECTIVE SHEET | 日東電工株式会社 | 2020-07-02 | — | — | WO | disclosed |
| WO-2019151192-A1 | METHOD FOR PEELING ADHESIVE SHEET | 日東電工株式会社 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019151194-A1 | ADHESIVE SHEET AND PEELING METHOD FOR ADHESIVE SHEET | 日東電工株式会社 | 2019-08-08 | — | — | WO | disclosed |