SCHEMBL21391606

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21391672	0.88	NR1H4 (0.45)	ENPP3ENPP1NR1H4MEN1KMT2A
	SCHEMBL21387986	0.86	MEN1 (0.42)	MEN1KMT2ARAB9AALDH1A1MAPT
	SCHEMBL24253132	0.85	MEN1 (0.45)	ENPP3ENPP1NR1H4MEN1KMT2A
	SCHEMBL28196231	0.84	ENPP3 (0.54)	ENPP3ENPP1ESR1ESR2MEN1
	SCHEMBL21391650	0.82	CYP19A1 (0.50)	MEN1KMT2ARAB9AALDH1A1MAPT
	SCHEMBL21391609	0.81	MEN1 (0.40)	MEN1KMT2ARAB9AALDH1A1MAPT
	SCHEMBL18732400	0.80	ENPP3 (0.55)	ENPP3ENPP1ESR1ESR2MEN1
	SCHEMBL12258363	0.80	MEN1 (0.53)	ENPP3ENPP1ESR1ESR2MEN1
	SCHEMBL26416883	0.80	CYP19A1 (0.49)	MEN1KMT2ARAB9AALDH1A1MAPT
	SCHEMBL21391674	0.80	MEN1 (0.45)	MEN1KMT2ARAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.