SCHEMBL21391672

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24253132	0.91	MEN1 (0.45)	NR1H4MEN1KMT2AALDH1A1MAPT
	SCHEMBL25803018	0.90	NR1H4 (0.39)	NR1H4MEN1KMT2AALDH1A1MAPT
	SCHEMBL21391745	0.89	NR1H4 (0.43)	NR1H4MEN1KMT2AALDH1A1MAPT
	SCHEMBL21391606	0.88	ENPP3 (0.41)	NR1H4MEN1KMT2AALDH1A1MAPT
	SCHEMBL21391674	0.86	MEN1 (0.45)	MEN1KMT2AALDH1A1MAPTKDM4E
	SCHEMBL23268828	0.84	MEN1 (0.50)	MEN1KMT2AALDH1A1MAPTKDM4E
	SCHEMBL18731826	0.84	MEN1 (0.52)	NR1H4MEN1KMT2AALDH1A1MAPT
	SCHEMBL20174196	0.83	NR1H4 (0.48)	NR1H4MEN1KMT2AALDH1A1MAPT
	SCHEMBL24253147	0.82	MEN1 (0.38)	NR1H4MEN1KMT2AALDH1A1MAPT
	SCHEMBL25629741	0.82	MEN1 (0.38)	NR1H4MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.