SCHEMBL2155177

SCHEMBL2155177

CC(C)(C)Oc1c[c]cc(OC(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.33
RIPK1 Q13546 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16959383 0.91 ALDH1A1 (0.42) KIF11ALDH1A1
SCHEMBL16953037 0.87 NQO1 (0.39) ALDH1A1
SCHEMBL16950791 0.86 GABRA1 (0.30) KIF11
SCHEMBL16953097 0.86 KIF11 (0.30) KIF11
SCHEMBL16952350 0.86 KIF11 (0.30) KIF11
SCHEMBL16957081 0.85 ALDH1A1 (0.31) ALDH1A1
SCHEMBL16959002 0.84
SCHEMBL16951108 0.84
SCHEMBL16961743 0.84
SCHEMBL5841243 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7811637-B2 Silicon-containing polymer, process for producing the same, heat-resistant resin composition, and heat-resistant film TOAGOSEI CO., LTD. (JP) 2010-10-12 US claimed
CN-114380928-B Preparation method and application of mono-and bis-phenylthioimine vanadium olefin polymerization catalyst 吉林大学 2022-09-30 CN disclosed
CN-114380928-A Preparation method and application of mono-and bis-phenylthioimine vanadium olefin polymerization catalyst 吉林大学 2022-04-22 CN disclosed
EP-2900645-B1 HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2019-08-21 EP disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
EP-2858750-B1 PHOSPHINYL GUANIDINE COMPOUNDS, CHROMIUM SALT COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-13 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
US-9962689-B2 Phosphinyl formamidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-05-08 US disclosed
US-20170305945-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP 2017-10-26 US disclosed
US-9732106-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-08-15 US disclosed
US-20120172645-A1 Olefin Oligomerization catalysts and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-07-05 US disclosed
WO-2011082192-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-07-07 WO disclosed
US-20100261924-A1 ASYMMETRIC CATALYST AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOLS USING THE SAME KANTO KAGAKU KABUSHIKI KAISHA (JP) 2010-10-14 US disclosed
EP-2239057-A1 Asymmetric catalyst and process for preparing optically active alcohols using the same Kanto Kagaku Kabushiki Kaisha (JP) 2010-10-13 EP disclosed
US-7811637-B2 Silicon-containing polymer, process for producing the same, heat-resistant resin composition, and heat-resistant film TOAGOSEI CO., LTD. (JP) 2010-10-12 US disclosed
EP-2159249-A1 Silicon-containing polymer and method for manufacturing the same, heat-resistant resin composition, and heat-resistant film TOAGOSEI CO., LTD. (JP) 2010-03-03 EP disclosed
US-20100029841-A1 SILICONE-CONTAINING POLYMER AND A HEAT-RESISTANT RESIN COMPOSITION COMPRISING THE SILICON-CONTAINING POLYMER TOAGOSEI CO., LTD. (JP) 2010-02-04 US disclosed
US-20070134424-A1 excellent in alkali solubility despite high molecular weight; resists, aerospace, semiconductors; polycondensing alkoxy- or hydroxyphenylalkyltriethoxysilane and tetraethoxysilane with hexamethyldisiloxane to endcap with trimethylsilanol and no toxic gas generated; polysiloxane and polysilicate copolymer TOAGOSEI CO., LTD. (JP) 2007-06-14 US disclosed
EP-1650250-A1 SILICON-CONTAINING POLYMER, PROCESS FOR RPODUCING THE SAME, HEAT-RESISTANT RESIN COMPOSITION, AND HEAT-RESISTANT FILM TOAGOSEI CO., LTD. (JP) 2006-04-26 EP disclosed
EP-1277758-A1 PHOSPHORUS COMPOUND Daicel Chemical Industries, Ltd. (JP) 2003-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261924-A1 ASYMMETRIC CATALYST AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOLS USING THE SAME ADH1A, ADH1C, ADH5 KIF11 1882/4885RIPK1 2805/4885ALDH1A1 80/4885
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 KIF11 3803/4885RIPK1 216/4885ALDH1A1 4849/4885
US-20120172645-A1 Olefin Oligomerization catalysts and Methods of Making and Using Same COG7, COG8, COG4 KIF11 3967/4885RIPK1 472/4885ALDH1A1 2928/4885
US-20170305945-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 KIF11 3803/4885RIPK1 216/4885ALDH1A1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.