Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270671 | 0.88 | RORC (0.39) | LPAR1RORCLPAR3RORBKDR | |
| SCHEMBL22270885 | 0.86 | RORC (0.35) | RORCKDR | |
| SCHEMBL22270563 | 0.81 | WNT3A (0.39) | RORCKDR | |
| SCHEMBL22270886 | 0.78 | L3MBTL1 (0.35) | — | |
| SCHEMBL22270668 | 0.78 | KDR (0.36) | RORCKDR | |
| SCHEMBL22270887 | 0.75 | KDM4E (0.40) | — | |
| SCHEMBL22270537 | 0.75 | MAPT (0.36) | KDR | |
| SCHEMBL22270880 | 0.74 | LMNA (0.37) | KDR | |
| SCHEMBL19205794 | 0.74 | RORC (0.44) | LPAR1RORCLPAR2LPAR3RORB | |
| SCHEMBL18447804 | 0.74 | RORC (0.44) | LPAR1RORCLPAR2LPAR3RORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |