Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.38 |
| ▸ | WNT3A | P56704 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270603 | 0.84 | MAPT (0.35) | PDGFRBMAPTLMNATP53KDM4E | |
| SCHEMBL22270563 | 0.80 | WNT3A (0.39) | MAPTLMNATP53WNT3AKDM4E | |
| SCHEMBL22270880 | 0.78 | LMNA (0.37) | MAPTLMNATP53WNT3AALDH1A1 | |
| SCHEMBL22270537 | 0.75 | MAPT (0.36) | MAPTLMNATP53WNT3AALDH1A1 | |
| SCHEMBL19205622 | 0.74 | WNT3A (0.46) | AOC3WNT3A | |
| SCHEMBL22271066 | 0.72 | RORC (0.35) | MAPT | |
| SCHEMBL22270885 | 0.72 | RORC (0.35) | MAPTLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL22270887 | 0.71 | KDM4E (0.40) | MAPTKDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL22270668 | 0.71 | KDR (0.36) | MAPTLMNAWNT3AALDH1A1SMN1; SMN2 | |
| SCHEMBL22270671 | 0.71 | RORC (0.39) | WNT3AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |