Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31588864 | 0.91 | PYCR1 (0.50) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL3157181 | 0.85 | CYP2C19 (0.59) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL3156936 | 0.85 | CRHBP (0.54) | CYP1A2CYP2D6CYP2C9CYP2C19CRHBP | |
| SCHEMBL29336516 | 0.81 | PYCR1 (0.59) | KCNH2CRHBPCRHR2PYCR1LOXL2 | |
| SCHEMBL3161766 | 0.80 | CYP1A2 (0.75) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL15392240 | 0.78 | LOXL2 (0.59) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL20871858 | 0.77 | CNR2 (0.49) | KCNH2PYCR1HRH3 | |
| SCHEMBL28042128 | 0.77 | ALDH1A1 (0.52) | CYP2D6CYP2C9CYP2C19KCNH2CRHBP | |
| SCHEMBL1206139 | 0.76 | HRH3 (0.58) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL22340499 | 0.76 | PYCR1 (0.64) | PYCR1KDM4EALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | Universite Paris-Saclay (FR) | 2021-06-15 | — | — | US | disclosed |
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | Universite Paris-Saclay (FR) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | ADH1C, ADH1A, ADH5 | CYP1A2 204/4885CYP2D6 2652/4885CYP2C9 1888/4885 |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | ADH1C, PNMT, ADH1A | CYP1A2 169/4885CYP2D6 2314/4885CYP2C9 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.