SCHEMBL22458171

SCHEMBL22458171

C#C/C=C\C(=C/C)c1ccc(-c2cccc(-c3cc(C#N)cc(-c4ccc(-c5cccc(-c6ccc(-c7ccccc7)cc6)c5)cc4)c3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN5 P54829 1/20 0.38
▸ KAT6A Q92794 2/20 0.37
▸ XDH P47989 1/20 0.35
▸ SLC22A12 Q96S37 1/20 0.35
▸ FFAR2 O15552 1/20 0.35
▸ PLAU P00749 2/20 0.34
▸ ADAMTS4 O75173 1/20 0.33
▸ CTSL P07711 1/20 0.33
▸ CTSB P07858 1/20 0.33
▸ CTSS P25774 1/20 0.33
▸ CTSK P43235 1/20 0.33
▸ SLC6A7 Q99884 1/20 0.33
▸ MMP12 P39900 1/20 0.33
▸ MMP13 P45452 1/20 0.33
▸ GABRA1 P14867 1/20 0.33
▸ GABRG2 P18507 1/20 0.33
▸ GABRB3 P28472 1/20 0.33
▸ GABRA5 P31644 1/20 0.33
▸ GABRA3 P34903 1/20 0.33
▸ GRIA2 P42262 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26437500 0.84 SMN1; SMN2 (0.40) —
SCHEMBL19831560 0.75 MAOB (0.33) —
SCHEMBL17775874 0.75 PTPN5 (0.49) PTPN5KAT6AXDHSLC22A12MMP12
SCHEMBL26216515 0.72 KDM4E (0.33) —
SCHEMBL18411464 0.72 GABRA1 (0.49) PTPN5XDHSLC22A12GABRA1GABRG2
SCHEMBL18411439 0.72 GABRA1 (0.49) PTPN5XDHSLC22A12GABRA1GABRG2
SCHEMBL18410831 0.71 PDK2 (0.34) —
SCHEMBL23020221 0.71 CYP1A2 (0.41) ALDH1A3CLK4
SCHEMBL26380790 0.71 NR4A2 (0.33) —
SCHEMBL29511815 0.70 XDH (0.56) PTPN5XDHSLC22A12MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371361-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY OF SOUTHERN CALIFORNIA 2023-11-16 — — US disclosed
US-20230303605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-09-28 — — US disclosed
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 — — US disclosed
US-20230292608-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-09-14 — — US disclosed
US-20230279029-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 — — US disclosed
US-20230192730-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 — — US disclosed
US-11683981-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-20 — — US disclosed
US-20230129581-A1 PLASMONIC OLEDs AND VERTICAL DIPOLE EMITTERS UNIVERSAL DISPLAY CORPORATION 2023-04-27 — — US disclosed
US-20230010166-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-12 — — US disclosed
US-11114624-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-09-07 — — US disclosed
US-20210028376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-28 — — US disclosed
US-20200361974-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-19 — — US disclosed
US-20200303657-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP PTPN5 4408/4885KAT6A 3728/4885XDH 855/4885
US-11114624-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND PTPN5 4824/4885KAT6A 1721/4885XDH 370/4885
US-20230371361-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ODC1, OTC, AOC2 PTPN5 4866/4885KAT6A 2088/4885XDH 141/4885
US-20200303657-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, JUND PTPN5 4824/4885KAT6A 1721/4885XDH 370/4885
US-20230192730-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, AOC2 PTPN5 4799/4885KAT6A 1212/4885XDH 361/4885
US-20230292608-A1 Organic Electroluminescent Materials and Devices ICMT, INMT, PNMT PTPN5 4742/4885KAT6A 2101/4885XDH 1055/4885
US-20230279029-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, EHD1 PTPN5 4588/4885KAT6A 3112/4885XDH 108/4885
US-20230010166-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, CHRM1, OSBPL8 PTPN5 4426/4885KAT6A 2665/4885XDH 324/4885
US-11683981-B2 Organic electroluminescent materials and devices OXER1, CHRM1, OSBPL8 PTPN5 4426/4885KAT6A 2665/4885XDH 324/4885
US-20200361974-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, TRPM2, ORAI2 PTPN5 4169/4885KAT6A 4274/4885XDH 3586/4885
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LMNB1, RPS8 PTPN5 4715/4885KAT6A 3009/4885XDH 301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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