Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433388 | 1.00 | ROCK1 (0.42) | ROCK1ABL1KDM4EGAAMAPT | |
| SCHEMBL28501568 | 0.81 | HCAR3 (0.41) | ROCK1ABL1KDM4EGAAMAPT | |
| SCHEMBL22926205 | 0.75 | KDM4E (0.42) | ROCK1ABL1KDM4EGAAALOX15 | |
| SCHEMBL29417994 | 0.75 | GAA (0.42) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL1964973 | 0.75 | GAA (0.42) | KDM4EGAAMAPTNPC1RAB9A | |
| SCHEMBL1002255 | 0.75 | MPO (0.43) | ROCK1KDM4EALOX15GFERADAM17 | |
| Hydrochloric Acid SCHEMBL22395324 | 0.73 | MPO (0.42) | ROCK1KDM4EALOX15GFERADAM17 | |
| SCHEMBL25201725 | 0.73 | ROCK1 (0.44) | ROCK1ABL1GAAMAPTHCRTR1 | |
| SCHEMBL30005327 | 0.72 | CHRNB2 (0.39) | ROCK1ALOX15GFERADAM17LMNA | |
| SCHEMBL24665317 | 0.72 | CHRNB2 (0.39) | ROCK1ALOX15GFERADAM17LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230389550-A1 | HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-07 | — | — | US | claimed |
| US-20230063447-A1 | HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-02 | — | — | US | claimed |
| US-20210386070-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-16 | — | — | US | claimed |
| EP-3919486-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-12-08 | — | — | EP | claimed |
| EP-3784661-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-03-03 | — | — | EP | claimed |
| CN-112204021-A | Novel heteroaryltriazole and heteroaryltetrazole compounds as pesticides | 拜耳公司 | 2021-01-08 | — | — | CN | claimed |
| US-20250186433-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | EPIVARIO, INC. | 2025-06-12 | — | — | US | disclosed |
| US-12171229-B2 | Heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2024-12-24 | — | — | US | disclosed |
| US-12133852-B2 | ACSS2 inhibitors and methods of use thereof | EPIVARIO, INC. (US) | 2024-11-05 | — | — | US | disclosed |
| CN-112204021-B | Novel heteroaryl triazoles and heteroaryl tetrazoles as pesticides | 拜耳公司 | 2024-05-28 | — | — | CN | disclosed |
| US-11864557-B2 | Heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-09 | — | — | US | disclosed |
| US-20230389550-A1 | HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-07 | — | — | US | disclosed |
| EP-3784661-B1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AG (DE) | 2023-11-22 | — | — | EP | disclosed |
| US-20210386070-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-16 | — | — | US | disclosed |
| EP-3919486-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-12-08 | — | — | EP | disclosed |
| EP-3919486-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-12-08 | — | — | EP | disclosed |
| EP-3784661-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-03-03 | — | — | EP | disclosed |
| CN-112204021-A | Novel heteroaryltriazole and heteroaryltetrazole compounds as pesticides | 拜耳公司 | 2021-01-08 | — | — | CN | disclosed |
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186433-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | ACSS2, GLS2, ADSS2 | ROCK1 2926/4885ABL1 4450/4885KDM4E 2609/4885 |
| US-20210386070-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | CYP4F3, TARS2, CYP4X1 | ROCK1 3418/4885ABL1 1245/4885KDM4E 2663/4885 |
| US-11864557-B2 | Heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides | CYP4F3, TARS2, TH | ROCK1 3584/4885ABL1 956/4885KDM4E 2912/4885 |
| US-20230063447-A1 | HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | CYP4F3, TARS2, TH | ROCK1 3584/4885ABL1 956/4885KDM4E 2912/4885 |
| US-12171229-B2 | Heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides | CYP4F3, TARS2, TH | ROCK1 3584/4885ABL1 956/4885KDM4E 2912/4885 |
| US-20230389550-A1 | HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | CYP4F3, TARS2, TH | ROCK1 3584/4885ABL1 956/4885KDM4E 2912/4885 |
| US-12133852-B2 | ACSS2 inhibitors and methods of use thereof | ACSS2, GLS2, ADSS2 | ROCK1 2926/4885ABL1 4450/4885KDM4E 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.