Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP2 | P42575 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22904553 | 0.81 | TDP2 (0.39) | PPARGPPARDPPARACASP3CASP7 | |
| SCHEMBL22904147 | 0.81 | MAOB (0.38) | ADORA2AMAOAMAOBLMNASMN1; SMN2 | |
| SCHEMBL22904452 | 0.71 | TDP2 (0.38) | CASP3CASP7CASP6CASP8 | |
| SCHEMBL22904454 | 0.68 | TDP2 (0.36) | — | |
| SCHEMBL22904457 | 0.68 | TDP2 (0.36) | — | |
| SCHEMBL22909125 | 0.66 | SOD1 (0.40) | STK10SLKMAOAMAOBLMNA | |
| SCHEMBL5506330 | 0.66 | MAOA (0.51) | STK10SLKADORA2AMAOAMAOB | |
| SCHEMBL22904554 | 0.65 | LMNA (0.44) | LMNASMN1; SMN2CASP3CASP2CASP7 | |
| SCHEMBL16628857 | 0.65 | MAOA (0.41) | STK10SLKMAOAMAOBLMNA | |
| SCHEMBL22904576 | 0.64 | DAO (0.50) | STK10SLKMAOAMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011631-A1 | FUSED-GLUTARIMIDE CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |