SCHEMBL229249

SCHEMBL229249

Cc1cc(C)cc(CC(NC2=NCCS2)c2cccc(C)c2C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.40
NPC1 O15118 8/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 3/20 0.40
TAAR1 Q96RJ0 1/20 0.40
SMN1; SMN2 Q16637 7/20 0.39
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1107826 0.89 ALDH1A1 (0.40) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL3415431 0.88 LMNA (0.47) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL1107882 0.86 KMT2A (0.38) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL1096470 0.84 ATM (0.41) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL12264045 0.84 HSD17B10 (0.45) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL12264052 0.84 RAB9A (0.37) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL1041093 0.84 RAB9A (0.37) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL15310036 0.84 LMNA (0.38) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL12264048 0.83 NPC1 (0.40) RAB9ANPC1KDM4ELMNATAAR1
SCHEMBL12264050 0.82 NPC1 (0.37) RAB9ANPC1KDM4ELMNATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
US-20190159451-A1 ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-05-30 US claimed
EP-3395171-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-10-31 EP claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP claimed
EP-2793578-B1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-06-06 EP claimed
EP-2925142-B1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2018-01-31 EP claimed
US-9867377-B2 Composition comprising a biological control agent and an insecticide BAYER CROPSCIENCE AG (DE) 2018-01-16 US claimed
US-20170265479-A1 COMPOSITION COMPRISING BIOLOGICAL CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2017-09-21 US claimed
US-9693565-B2 Composition comprising biological control agents BAYER CROPSCIENCE AG (DE) 2017-07-04 US claimed
WO-2012143125-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND BAYER CROPSCIENCE AG (DE) 2012-10-26 WO claimed
EP-2467021-A1 3-[1-(3-HALOALKYL)-TRIAZOLYL]-PHENYL-SULFIDE DERIVATIVES FOR USE AS ACARICIDES AND INSECTICIDES Bayer CropScience AG (DE) 2012-06-27 EP claimed
WO-2012082548-A2 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2012082542-A2 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2012076471-A1 INSECTICIDAL MIXTURES WITH IMPROVED PROPERTIES BAYER CROPSCIENCE AG (DE) 2012-06-14 WO claimed
US-20120083463-A1 Insecticidal and Fungicidal Active Compound Combinations BAYER CROPSCIENCE AG (DE) 2012-04-05 US claimed
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-12-22 US claimed
WO-2011029506-A1 3-[1-(3-HALOALKYL)-TRIAZOLYL]-PHENYL-SULFIDE DERIVATIVES FOR USE AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2011-03-17 WO claimed
US-20110046194-A1 3-Triazolylphenyl-substituted sulphide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2011-02-24 US claimed
US-20110045104-A1 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2011-02-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190159451-A1 ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS BROX, CAT, MPG RAB9A 2724/4885NPC1 2296/4885KDM4E 3723/4885
US-20120083463-A1 Insecticidal and Fungicidal Active Compound Combinations DDT, ACHE, CYP4B1 RAB9A 637/4885NPC1 2387/4885KDM4E 719/4885
US-20110045104-A1 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides ATL3, PDIA3, NAT1 RAB9A 929/4885NPC1 601/4885KDM4E 4319/4885
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties ACHE, ACAT1, ACAT2 RAB9A 332/4885NPC1 843/4885KDM4E 3132/4885
US-20110046194-A1 3-Triazolylphenyl-substituted sulphide derivatives as acaricides and insecticides CYP4B1, ARSA, C1S RAB9A 1000/4885NPC1 2397/4885KDM4E 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.