Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21173939 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1HPGDMEN1CYP3A4 | |
| SCHEMBL34626 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1CYP3A4 | |
| SCHEMBL5546185 | 0.87 | HTT (0.39) | KDM4EALDH1A1HPGDMEN1CYP3A4 | |
| SCHEMBL2230706 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HPGDMEN1CYP3A4 | |
| Sulfuric Acid SCHEMBL5169476 | 0.85 | FDPS (0.42) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL34909 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1HPGDMEN1CYP3A4 | |
| Sulfuric Acid SCHEMBL5930927 | 0.83 | FDPS (0.41) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3187868 | 0.83 | FDPS (0.41) | MEN1KMT2ASMN1; SMN2 | |
| Sulfuric Acid SCHEMBL5930932 | 0.82 | FDPS (0.43) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2295678 | 0.82 | FDPS (0.43) | MEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003822-B2 | Process for continuous carbonylation by supported ionic liquid-phase catalysis | WACKER CHEMIE AG (DE) | 2011-08-23 | — | — | US | claimed |
| EP-1883616-B1 | A PROCESS FOR CONTINUOUS CARBONYLATION BY SUPPORTED IONIC LIQUID-PHASE CATALYSIS | WACKER CHEMIE AG (DE) | 2009-09-30 | — | — | EP | claimed |
| US-20090030229-A1 | Process for continuous carbonylation by supported ionic liquid-phase catalysis | WACKER CHEMIE AG (DE) | 2009-01-29 | — | — | US | claimed |
| EP-1883616-A1 | A PROCESS FOR CONTINUOUS CARBONYLATION BY SUPPORTED IONIC LIQUID-PHASE CATALYSIS | Danmarks Tekniske Universitet (DK) | 2008-02-06 | — | — | EP | claimed |
| EP-1663921-B1 | METHOD FOR PRODUCING HALOALKANES FROM ALCOHOLS | BASF AG (DE) | 2007-05-02 | — | — | EP | claimed |
| US-20070055084-A1 | Method for producing haloalkanes from alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-08 | — | — | US | claimed |
| WO-2006122563-A1 | A PROCESS FOR CONTINUOUS CARBONYLATION BY SUPPORTED IONIC LIQUID-PHASE CATALYSIS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2006-11-23 | — | — | WO | claimed |
| EP-1650328-B1 | METHOD FOR FORMING OXIDE FILM ON METAL SURFACE USING IONIC LIQUID, ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF | KANEKA CORP (JP) | 2016-10-19 | — | — | EP | disclosed |
| EP-2540875-A1 | Electrolytic capacitor including ionic liquid in electrolyte | KANEKA CORPORATION (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8014128-B2 | Method for forming oxide film on metal surface using ionic liquid, electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8003822-B2 | Process for continuous carbonylation by supported ionic liquid-phase catalysis | WACKER CHEMIE AG (DE) | 2011-08-23 | — | — | US | disclosed |
| US-7746623-B2 | Electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7659430-B2 | Method for separating hydrogen chloride and phosgene | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-09 | — | — | US | disclosed |
| US-20070055084-A1 | Method for producing haloalkanes from alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-08 | — | — | US | disclosed |
| WO-2006122563-A1 | A PROCESS FOR CONTINUOUS CARBONYLATION BY SUPPORTED IONIC LIQUID-PHASE CATALYSIS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2006-11-23 | — | — | WO | disclosed |
| US-20060181835-A1 | Method for forming oxide film on metal surface using ionic liquid, electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2006-08-17 | — | — | US | disclosed |
| EP-1650328-A1 | METHOD FOR FORMING OXIDE FILM ON METAL SURFACE USING IONIC LIQUID, ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF | KANEKA CORPORATION (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-6995293-B2 | Method for the production of aldehydes | CELANESE CHEMICALS EUROPE GMBH (DE) | 2006-02-07 | — | — | US | disclosed |
| US-20050085671-A1 | Method for the production of aldehydes | DRACHENFELSSEE 521. VV GMBH (TO BE RENAMED OXEA DEUTSCHLAND GMBH) (DE) | 2005-04-21 | — | — | US | disclosed |
| EP-1400504-A1 | Process for the preparation of aldehydes | Celanese Chemicals Europe GmbH (DE) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055084-A1 | Method for producing haloalkanes from alcohols | ADH1C, HDHD5, ADH5 | KDM4E 2710/4885ALDH1A1 493/4885HPGD 796/4885 |
| US-20090030229-A1 | Process for continuous carbonylation by supported ionic liquid-phase catalysis | SOD1, OGDH, LPO | KDM4E 442/4885ALDH1A1 547/4885HPGD 1805/4885 |
| US-20050085671-A1 | Method for the production of aldehydes | ACSL3, ACSL5, TST | KDM4E 3715/4885ALDH1A1 116/4885HPGD 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.