Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23031878 | 0.84 | LMNA (0.44) | HDAC1HDAC8CHRM2MEN1KMT2A | |
| SCHEMBL21300883 | 0.78 | LOXL2 (0.47) | HDAC6 | |
| SCHEMBL23031880 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL23032115 | 0.74 | L3MBTL1 (0.58) | MEN1KMT2A | |
| SCHEMBL23032003 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL22044273 | 0.71 | GRIN2B (0.44) | KMT2A | |
| SCHEMBL23031867 | 0.70 | CA2 (0.43) | ANPEPMEN1KMT2A | |
| SCHEMBL24529806 | 0.70 | ALOX15 (0.45) | HDAC1 | |
| SCHEMBL22815269 | 0.69 | KDM1A (0.48) | OPRD1MEN1KMT2A | |
| SCHEMBL24267754 | 0.69 | NAMPT (0.49) | HDAC1HDAC6MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034924-A1 | TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS | BIOGEN MA INC. (US) | 2021-02-25 | — | — | WO | disclosed |