Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21137817 | 0.81 | GAA (0.42) | GAAHDAC1MAPTLMNAMEN1 | |
| SCHEMBL17779609 | 0.68 | MAPT (0.41) | HDAC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21138155 | 0.68 | EP300 (0.48) | HDAC1MAPTLMNAMEN1KMT2A | |
| SCHEMBL30625925 | 0.67 | LMNA (0.47) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL17775442 | 0.67 | ALDH1A1 (0.47) | GAAHDAC1MAPTLMNAMEN1 | |
| SCHEMBL16371049 | 0.66 | MAPT (0.48) | GAAHDAC1MAPTLMNAALDH1A1 | |
| SCHEMBL30625922 | 0.65 | HDAC3 (0.48) | HDAC1MAPTMEN1KMT2AHTT | |
| SCHEMBL20786981 | 0.64 | MITF (0.42) | GAAHDAC1MAPTLMNAMEN1 | |
| SCHEMBL20787640 | 0.64 | NPC1 (0.49) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL17795709 | 0.63 | EP300 (0.51) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019615-B1 | CYSTOBACTAMIDES | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |