SCHEMBL232638

SCHEMBL232638

[O-][n+]1ccc2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.46
BCHE P06276 13/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358798 1.00 ACHE (0.46) ACHEBCHE
Methyl Alcohol SCHEMBL9624379 0.93 ACHE (0.42) ACHEBCHE
SCHEMBL9902394 0.85 ATM (0.44) ACHEBCHE
Isoquinoline SCHEMBL5264460 0.82 ACHE (0.37) ACHEBCHE
SCHEMBL13659534 0.77 ALDH1A1 (0.52)
SCHEMBL5894087 0.71 CYP2A6 (0.44) ACHEBCHE
SCHEMBL25252937 0.70 CYP1A2 (0.52)
SCHEMBL31426083 0.70 CYP2A6 (0.46) ACHE
SCHEMBL31228277 0.70 CYP1A2 (0.46) ACHE
SCHEMBL23088139 0.70 CYP2A6 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326709-A1 THE MICROWAVE-ASSISTED CATALYTIC AMIDATION OF ORGANIC AMINES WITH CARBOXYLIC ACIDS PURDUE RESEARCH FOUNDATION (US) 2025-10-23 US claimed
CN-120058605-A Synthesis method of nitrogen ortho-substituted aryl ether of nitrogen-containing heterocycle 新疆大学 2025-05-30 CN claimed
WO-2025059054-A1 PROCESS FOR PREPARING (2S,4S,4'S,6S)-2-METHYL-6-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-2',-(TRIELUOROMETHYL)-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO [2,3-C] PYRAN] -4'-OL VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-03-20 WO claimed
CN-118345390-A Method for preparing carbonyl compound by electrocatalytic oxidation of benzyl C-H bond by pyridine nitrogen oxide 浙江大学 2024-07-16 CN claimed
CN-113966318-B Compound for chromatographic separation of rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2024-06-18 CN claimed
US-11932592-B2 Process for the transformation of primary aliphatic alcohols into higher aliphatic alcohols Alma Mater Studiorum—Universita' di Bologna (IT) 2024-03-19 US claimed
EP-3774706-B1 IMPROVED PROCESS FOR THE TRANSFORMATION OF PRIMARY ALIPHATIC ALCOHOLS INTO HIGHER ALIPHATIC ALCOHOLS UNIV BOLOGNA ALMA MATER STUDIORUM (IT) 2023-12-20 EP claimed
EP-4186507-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF FIBROTIC DISEASES Galapagos N.V. (BE) 2023-05-31 EP claimed
CN-112574107-B Synthesis method of atropisomeric 1-arylisoquinoline N-oxide and derivatives thereof 浙江工业大学 2023-04-07 CN claimed
CN-113966318-A Compound for chromatographic separation of rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2022-01-21 CN claimed
US-5714493-A ANTIINFLAMMATORY AGENT RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-02-03 US claimed
CN-1145360-A Substituted benzyloxy carbonyl guanidine, its prepn. method, and application of the same as medicament and medicament containing the same HOECHST AG (DE) 1997-03-19 CN claimed
EP-0741731-A1 PROCESS FOR EPOXIDISING PROCHIRAL OLEFINS AND A CATALYST THEREFOR AND INTERMEDIATES FOR MAKING THE CATALYST SMITHKLINE BEECHAM PLC (GB) 1996-11-13 EP claimed
WO-1995021172-A1 PROCESS FOR EPOXIDISING PROCHIRAL OLEFINS AND A CATALYST THEREFOR AND INTERMEDIATES FOR MAKING THE CATALYST SMITHKLINE BEECHAM P.L.C. (GB) 1995-08-10 WO claimed
EP-0584222-A4 BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE RHONE POULENC RORER INT (US) 1994-07-06 EP claimed
EP-0584222-A1 BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE. RHONE POULENC RORER INT (US) 1994-03-02 EP claimed
US-5175157-A Cardiovascular disorders BOEHRINGER INGELHEIM GMBH (DE) 1992-12-29 US claimed
WO-1992020642-A1 BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-11-26 WO claimed
EP-0224086-B1 SUBSTITUTED BENZYL ETHERS BAYER AG (DE) 1990-10-24 EP claimed
US-4076713-A Indanthrene dyes PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-02-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11932592-B2 Process for the transformation of primary aliphatic alcohols into higher aliphatic alcohols ADH1A, ADH5, ADH1C ACHE 2426/4885BCHE 3210/4885
US-20250326709-A1 THE MICROWAVE-ASSISTED CATALYTIC AMIDATION OF ORGANIC AMINES WITH CARBOXYLIC ACIDS NAAA, OAT, PAM ACHE 20/4885BCHE 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.