SCHEMBL2364062

SCHEMBL2364062

C=CCN(CC=C)C(O)C(=O)CC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2550190 0.71 SMPD2 (0.41) ALDH1A1TSHRMEN1KMT2ADPP4
SCHEMBL2733646 0.70 TSHR (0.30) TSHR
SCHEMBL787268 0.69 MEN1 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL15284768 0.67 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL7115253 0.67
Hydrochloric Acid SCHEMBL7975590 0.67 MEN1 (0.31) ALDH1A1MEN1KMT2A
SCHEMBL12923162 0.67
Bromide SCHEMBL11042423 0.67 MEN1 (0.31) ALDH1A1MEN1KMT2A
SCHEMBL10615339 0.67 ALDH1A1 (0.32) ALDH1A1
SCHEMBL89279 0.67 KMT2A (0.33) ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605107-B2 Method of preparing a supported hydrotreating catalyst EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-10-20 US claimed
US-7538066-B2 Method of preparing a hydrotreating catalyst on a support containing a rare earth metal EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-05-26 US claimed
US-20070082811-A1 Method of preparing a hydrotreating catalyst on a support containing a rare earth metal EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-04-12 US claimed
US-20070072765-A1 Method of preparing a supported hydrotreating catalyst EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-03-29 US claimed
US-9035107-B2 Dehydrogenation process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-19 US disclosed
US-9024078-B2 Dehydrogenation process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-05 US disclosed
US-8969639-B2 Dehydrogenation process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US disclosed
US-8884075-B2 Process for producing phenol EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-11-11 US disclosed
US-20140148620-A1 Process for Producing Phenol EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-05-29 US disclosed
US-20120323046-A1 Dehydrogenation Process EXXONMOBIL CHEMICAL PATENTS INC. 2012-12-20 US disclosed
EP-2531480-A1 DEHYDROGENATION PROCESS ExxonMobil Chemical Patents Inc. (US) 2012-12-12 EP disclosed
US-20120302798-A1 Dehydrogenation Process EXXONMOBIL CHEMICAL PATENTS INC. 2012-11-29 US disclosed
US-20120271077-A1 Dehydrogenation Process EXXONMOBILE CHEMICAL PATENTS INC. (US) 2012-10-25 US disclosed
WO-2012050665-A1 PROCESS FOR PRODUCING PHENOL EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-19 WO disclosed
WO-2011096992-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed
WO-2011096997-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed
WO-2011096994-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140148620-A1 Process for Producing Phenol HPD, CYP2J2, CYP2E1 ALDH1A1 1756/4885TSHR 4291/4885MEN1 3600/4885
US-20120271077-A1 Dehydrogenation Process ADH5, ADH1A, ADH1C ALDH1A1 40/4885TSHR 4452/4885MEN1 3747/4885
US-20120302798-A1 Dehydrogenation Process NDUFV1, NDUFV2, MAFG ALDH1A1 274/4885TSHR 4824/4885MEN1 1335/4885
US-20120323046-A1 Dehydrogenation Process ADH1A, ADH5, ADH1C ALDH1A1 85/4885TSHR 3816/4885MEN1 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.