Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 9/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770544 | 0.84 | S1PR1 (0.33) | FASNCDK2ABL1 | |
| SCHEMBL23770583 | 0.81 | RAF1 (0.36) | LRRK2ABL1 | |
| SCHEMBL23770596 | 0.77 | ADRB1 (0.41) | CDK2CCNA2CCNA1ABL1 | |
| SCHEMBL23770447 | 0.75 | SOS1 (0.34) | ABL1 | |
| SCHEMBL23770798 | 0.75 | ITGB2 (0.38) | LRRK2 | |
| SCHEMBL23770684 | 0.74 | ADRB2 (0.36) | JAK2JAK3 | |
| SCHEMBL23770701 | 0.74 | ATR (0.42) | — | |
| SCHEMBL23770652 | 0.72 | HSD11B1 (0.32) | ARCDK2 | |
| SCHEMBL19951400 | 0.71 | SCN9A (0.38) | FASNMAP3K12 | |
| SCHEMBL23770773 | 0.71 | ABL1 (0.37) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |