Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.62 |
| ▸ | PDE5A | O76074 | 3/20 | 0.59 |
| ▸ | METAP1 | P53582 | 2/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | AURKA | O14965 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490802 | 1.00 | NUDT1 (0.62) | NUDT1PDE5AMETAP1METAP2TP53 | |
| SCHEMBL1170747 | 0.80 | METAP1 (0.72) | NUDT1PDE5AMETAP1METAP2AURKA | |
| SCHEMBL939186 | 0.79 | NUDT1 (0.53) | NUDT1PDE5AMETAP1METAP2HPGD | |
| SCHEMBL27832091 | 0.78 | PDE10A (0.57) | NUDT1PDE5AMETAP1METAP2HPGD | |
| SCHEMBL24520478 | 0.77 | NUDT1 (0.60) | NUDT1PDE5AMETAP1METAP2TP53 | |
| SCHEMBL805045 | 0.77 | NUDT1 (0.60) | NUDT1PDE5AMETAP1METAP2TP53 | |
| SCHEMBL620579 | 0.77 | NUDT1 (0.60) | NUDT1PDE5AMETAP1METAP2TP53 | |
| SCHEMBL323981 | 0.77 | NUDT1 (0.60) | NUDT1PDE5AMETAP1METAP2TP53 | |
| SCHEMBL21389521 | 0.77 | NUDT1 (0.60) | NUDT1PDE5AMETAP1METAP2TP53 | |
| SCHEMBL6962055 | 0.77 | NUDT1 (0.60) | NUDT1PDE5AMETAP1METAP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014200885-A1 | PDE10a INHIBITORS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-18 | — | — | WO | claimed |
| US-20090253737-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED | 2009-10-08 | — | — | US | claimed |
| US-7276524-B2 | Pyridyl alkane acid amides as cytostatics and immunosuppressives | ASTELLAS DEUTSCHLAND GMBH (DE) | 2007-10-02 | — | — | US | claimed |
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | ASTELLAS PHARMA GMBH (DE) | 2007-09-20 | — | — | US | claimed |
| US-20070142377-A1 | Pyridyl Alkene and Pyridyl Alkine-Acid Amides as Cytostatics and Immunosuppressives | BIEDERMANN ELFI | 2007-06-21 | — | — | US | claimed |
| US-20040176605-A1 | New pyridyl alkane acid amides as cytostatics and immunosuppressives | KLINGE PHARMA GMBH | 2004-09-09 | — | — | US | claimed |
| US-20040029861-A1 | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression | KLINGE PHARMA GMBH | 2004-02-12 | — | — | US | claimed |
| US-20040009967-A1 | Pyridyl alkene- and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | KLINGE PHARMA GMBH | 2004-01-15 | — | — | US | claimed |
| US-20030162972-A1 | Pyridyl alkane acid amides as cytostatics and immunosupressives | KLINGE PHARMA GMBH | 2003-08-28 | — | — | US | claimed |
| JP-2000512652-A | — | — | 2000-09-26 | — | — | JP | claimed |
| EP-0912176-A1 | USE OF PYRIDYL ALKANE, PYRIDYL ALKENE AND/OR PYRIDYL ALKINE ACID AMIDES IN THE TREATMENT OF TUMORS OR FOR IMMUNOSUPPRESSION | Klinge Pharma GmbH (DE) | 1999-05-06 | — | — | EP | claimed |
| EP-0344414-B1 | 5-Substitued imidazo[4,5-c]pyridines | SEARLE & CO (US) | 1994-10-12 | — | — | EP | claimed |
| JP-63275582-A | — | — | None | — | — | JP | disclosed |
| CN-122094955-A | Compound, light-emitting device, display device, electronic apparatus, and lighting device | — | 2026-05-26 | — | — | CN | disclosed |
| US-20260059938-A1 | ORGANIC EL ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE | TORAY INDUSTRIES, INC. (JP) | 2026-02-26 | — | — | US | disclosed |
| EP-4656637-A1 | COMPOUND, AND LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, LIGHTING DEVICE AND PHOTOSENSITIZER EACH CONTAINING SAME | Toray Industries, Inc. (JP) | 2025-12-03 | — | — | EP | disclosed |
| WO-1999031060-A2 | PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES AS CYTOSTATICS AND IMMUNESUPPRESSANTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |
| EP-0912176-A1 | USE OF PYRIDYL ALKANE, PYRIDYL ALKENE AND/OR PYRIDYL ALKINE ACID AMIDES IN THE TREATMENT OF TUMORS OR FOR IMMUNOSUPPRESSION | Klinge Pharma GmbH (DE) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997048397-A1 | USE OF PYRIDYL ALKANE, PYRIDYL ALKENE AND/OR PYRIDYL ALKINE ACID AMIDES IN THE TREATMENT OF TUMORS OR FOR IMMUNOSUPPRESSION | KLINGE PHARMA GMBH (DE) | 1997-12-24 | — | — | WO | disclosed |
| JP-S63275582-A | PRODUCTION OF 1-AMINOIMIDAZO(4,5-B)PYRIDINE DERIVATIVE | NAADE KENKYUSHO:KK | 1988-11-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176605-A1 | New pyridyl alkane acid amides as cytostatics and immunosuppressives | ALK, ANXA1, ANXA11 | NUDT1 681/4885PDE5A 2884/4885METAP1 1400/4885 |
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | NFATC1, PDCD1, ACIN1 | NUDT1 320/4885PDE5A 3812/4885METAP1 1537/4885 |
| US-20040009967-A1 | Pyridyl alkene- and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | IDO1, ALK, ARG1 | NUDT1 617/4885PDE5A 3129/4885METAP1 1066/4885 |
| US-20090253737-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | TNNC1, TNNI3, TNNT2 | NUDT1 1089/4885PDE5A 1308/4885METAP1 3483/4885 |
| US-20040029861-A1 | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression | ALK, IDO1, PDXK | NUDT1 1681/4885PDE5A 3312/4885METAP1 708/4885 |
| US-20260059938-A1 | ORGANIC EL ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE | LEF1, LAGE3, EMC1 | NUDT1 3034/4885PDE5A 4134/4885METAP1 1575/4885 |
| US-20030162972-A1 | Pyridyl alkane acid amides as cytostatics and immunosupressives | ALK, TYMP, ANXA1 | NUDT1 664/4885PDE5A 3474/4885METAP1 1251/4885 |
| US-20070142377-A1 | Pyridyl Alkene and Pyridyl Alkine-Acid Amides as Cytostatics and Immunosuppressives | ALK, TYMP, PDCD1 | NUDT1 435/4885PDE5A 2945/4885METAP1 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.