Hydrochloric Acid

Hydrochloric Acid

SCHEMBL242206

Cn1c(Cl)[n+](C)c2ccccc21.[Cl-]

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERAP1 Q9NZ08 1/20 0.51
KDM4E B2RXH2 5/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 3/20 0.49
RAB9A P51151 3/20 0.49
HTT P42858 2/20 0.49
PTPN1 P18031 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.38
GPR3 P46089 1/20 0.37
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.35
GFER P55789 1/20 0.35
ALOX15 P16050 2/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29798986 1.00 ERAP1 (0.51) ERAP1KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL23641666 0.98 ERAP1 (0.49) ERAP1KDM4EMAPTALDH1A1L3MBTL1
Bromide SCHEMBL5145384 0.96 ERAP1 (0.47) ERAP1KDM4EMAPTALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL28409885 0.96 ERAP1 (0.47) ERAP1KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL31093213 0.91 ERAP1 (0.47) ERAP1KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL26106884 0.91 ERAP1 (0.47) ERAP1KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL1049324 0.75 ERAP1 (0.50) ERAP1KDM4EMAPTALDH1A1L3MBTL1
Water SCHEMBL21823213 0.73 ERAP1 (0.49) ERAP1KDM4EMAPTALDH1A1L3MBTL1
Iodide SCHEMBL9134481 0.73 PTPN1 (0.50) ERAP1KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL13173865 0.73 ERAP1 (0.53) ERAP1KDM4EMAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606634-B2 Antibody-pyrrolobenzodiazepine derivative conjugate which binds caludin-6 and claudin-9 DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-04-21 US disclosed
US-20260062461-A1 POPULATION OF ANTIBODIES COMPRISING HOMOGENEOUS ANTIBODIES EACH HAVING LEFT-RIGHT ASYMMETRIC SUGAR CHAINS, AND METHOD FOR PRODUCING SAME RIKEN (JP) 2026-03-05 US disclosed
EP-4703474-A1 ANTI-LRRC15 ANTIBODY Daiichi Sankyo Company, Limited (JP) 2026-03-04 EP disclosed
EP-4678192-A1 DOUBLE SITE-DIRECTED ANTIBODY-FUNCTIONAL MOLECULAR CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2026-01-14 EP disclosed
EP-4676483-A1 IMPROVED LINKER-PAYLOADS FOR ANTIBODY CONJUGATION, PHARMACEUTICAL COMPOSITIONS AND APPLICATIONS THEREOF OBI Pharma, Inc. (TW) 2026-01-14 EP disclosed
US-20260008803-A1 SIALIDASE-RESISTANT SACCHARIDE AND METHOD OF MAKING AND USING THE SAME ACADEMIA SINICA (TW) 2026-01-08 US disclosed
US-20250320255-A1 UNIVERSAL ADJUVANT FOR NASAL, ORAL, AND INTRAMUSCULAR DELIVERY OF VACCINES DESIGN ZYME LLC (US) 2025-10-16 US disclosed
EP-4615990-A1 GLYCOSYNTHASE VARIANTS FOR ANTIBODY-DRUG CONJUGATE ENGINEERING OBI Pharma, Inc. (TW) 2025-09-17 EP disclosed
US-12384811-B2 Sialidase-resistant saccharide and method of making and using the same ACADEMIA SINICA (TW) 2025-08-12 US disclosed
US-20250228958-A1 TSP1 INHIBITOR DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-17 US disclosed
EP-2407461-B1 PROCESS FOR PREPARATION OF 1-ALKYL-5-BENZOYL-1H-TETRAZOLE DERIVATIVES NIPPON SODA CO (JP) 2016-05-18 EP disclosed
EP-2392566-B1 METHOD FOR PRODUCING DICHLOROPYRAZINE DERIVATIVE NIPPON SODA CO (JP) 2016-03-02 EP disclosed
US-8835636-B2 Method for producing dichloropyrazine derivative NIPPON SODA CO., LTD. (JP) 2014-09-16 US disclosed
US-20140024832-A1 METHOD FOR PRODUCING DICHLOROPYRAZINE DERIVATIVE NIPPON SODA CO., LTD. (JP) 2014-01-23 US disclosed
US-8586741-B2 Method for producing dichloropyrazine derivative NIPPON SODA CO., LTD. (JP) 2013-11-19 US disclosed
US-8273781-B2 Process for preparation of 1-alkyl-5-benzoyl-1H-tetrazole derivatives NIPPON SODA CO., LTD. (JP) 2012-09-25 US disclosed
EP-2407461-A1 PROCESS FOR PREPARATION OF 1-ALKYL-5-BENZOYL-1H-TETRAZOLE DERIVATIVES Nippon Soda Co., Ltd. (JP) 2012-01-18 EP disclosed
US-20120004420-A1 PROCESS FOR PREPARATION OF 1-ALKYL-5-BENZOYL-1H-TETRAZOLE DERIVATIVES NIPPON SODA CO., LTD. (JP) 2012-01-05 US disclosed
EP-2392566-A1 METHOD FOR PRODUCING DICHLOROPYRAZINE DERIVATIVE Nippon Soda Co., Ltd. (JP) 2011-12-07 EP disclosed
US-20110275817-A1 METHOD FOR PRODUCING DICHLOROPYRAZINE DERIVATIVE NIPPON SODA CO., LTD. (JP) 2011-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062461-A1 POPULATION OF ANTIBODIES COMPRISING HOMOGENEOUS ANTIBODIES EACH HAVING LEFT-RIGHT ASYMMETRIC SUGAR CHAINS, AND METHOD FOR PRODUCING SAME FCGR2A, FCGR3B, FCGR1A ERAP1 132/4885KDM4E 1917/4885MAPT 3217/4885
US-20110275817-A1 METHOD FOR PRODUCING DICHLOROPYRAZINE DERIVATIVE CBR3, CBR1, HDHD5 ERAP1 3286/4885KDM4E 1636/4885MAPT 4539/4885
US-12606634-B2 Antibody-pyrrolobenzodiazepine derivative conjugate which binds caludin-6 and claudin-9 SIGLEC9, DSG1, VSIG8 ERAP1 2790/4885KDM4E 3835/4885MAPT 2345/4885
US-20120004420-A1 PROCESS FOR PREPARATION OF 1-ALKYL-5-BENZOYL-1H-TETRAZOLE DERIVATIVES KCNMA1, KCNA5, KCNK5 ERAP1 3517/4885KDM4E 180/4885MAPT 3696/4885
US-20250320255-A1 UNIVERSAL ADJUVANT FOR NASAL, ORAL, AND INTRAMUSCULAR DELIVERY OF VACCINES B3GNT2, ST3GAL3, MUC1 ERAP1 2758/4885KDM4E 4709/4885MAPT 3320/4885
US-20260008803-A1 SIALIDASE-RESISTANT SACCHARIDE AND METHOD OF MAKING AND USING THE SAME NEU2, ST6GAL1, NEU3 ERAP1 819/4885KDM4E 3272/4885MAPT 2734/4885
US-12384811-B2 Sialidase-resistant saccharide and method of making and using the same NEU2, NEU3, NEU1 ERAP1 434/4885KDM4E 2451/4885MAPT 4094/4885
US-20140024832-A1 METHOD FOR PRODUCING DICHLOROPYRAZINE DERIVATIVE CBR3, CBR1, HDHD5 ERAP1 3286/4885KDM4E 1636/4885MAPT 4539/4885
US-20250228958-A1 TSP1 INHIBITOR ANXA11, SERPINC1, NPR1 ERAP1 270/4885KDM4E 4118/4885MAPT 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.