Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 known ✓ | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838827 | 0.98 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL390493 | 0.98 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9735262 | 0.97 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL27782371 | 0.97 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| Water SCHEMBL8747163 | 0.97 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL5075926 | 0.97 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL2483874 | 0.97 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL2483869 | 0.97 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL10453008 | 0.87 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL10453009 | 0.87 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778172-B | Brilliant blue dye intermediate, reactive Brilliant blue dye and preparation method and application thereof | 湖北丽源科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-114086160-A | Copper surface chemical plating palladium activating solution and application thereof | 江苏艾森半导体材料股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-112778172-A | Novel brilliant blue dye intermediate, reactive brilliant blue dye and preparation method and application thereof | 湖北丽源科技股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-108997175-B | Method for preparing sodium m-nitrobenzenesulfonate and derivatives thereof by sulfonating chlorosulfonic acid | 金华双宏化工有限公司 | 2021-03-26 | — | — | CN | disclosed |
| EP-2376428-A2 | NEW INHIBITORS FOR TREATING DISEASES ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN | Universitätsklinikum Münster (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20110245335-A1 | NEW INHIBITORS FOR TREATING DISEASES ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN | UNIVERSITAETSKLINIKUM MUENSTER (DE) | 2011-10-06 | — | — | US | disclosed |
| WO-2010066909-A2 | NEW INHIBITORS FOR TREATING DISEASES ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN | Universitätsklinikum Münster (DE) | 2010-06-17 | — | — | WO | disclosed |
| CN-1169710-C | Process for preparing hydrogen sulfide | 唐培� | 2004-10-06 | — | — | CN | disclosed |
| CN-1342600-A | Process for preparing hydrogen sulfide | TANG PEIKUN (CN) | 2002-04-03 | — | — | CN | disclosed |
| US-5854179-A | Sulfur-substituted phenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245335-A1 | NEW INHIBITORS FOR TREATING DISEASES ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN | SLC10A1, ABCB11, HEXD | ALOX5 882/4885ALDH1A1 562/4885SMN1; SMN2 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.