SCHEMBL249539

SCHEMBL249539

COc1ccccc1CC=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
CHRM2 P08172 10/20 0.53
CHRM1 P11229 3/20 0.53
CHRM3 P20309 2/20 0.53
IDO1 P14902 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
GRIN1 Q05586 4/20 0.49
GRIN2A Q12879 4/20 0.49
BCHE P06276 4/20 0.49
ACHE P22303 4/20 0.49
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KDM4E B2RXH2 1/20 0.49
TP53 P04637 1/20 0.49
CHRM4 P08173 1/20 0.49
CYP3A4 P08684 1/20 0.49
CHRM5 P08912 1/20 0.49
CYP2D6 P10635 1/20 0.49
TSHR P16473 1/20 0.49
THPO P40225 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957820 1.00 ALDH1A1 (0.54) ALDH1A1CHRM2CHRM1CHRM3IDO1
SCHEMBL6177247 0.89 ALDH1A1 (0.47) ALDH1A1CHRM2CHRM1CHRM3IDO1
SCHEMBL1957955 0.85 HTR7 (0.46) ALDH1A1CHRM2CHRM1CHRM3IDO1
SCHEMBL27527691 0.84 CHRM2 (0.50) ALDH1A1CHRM2CHRM1CHRM3IDO1
SCHEMBL2167807 0.83 CXCL8 (0.42) ALDH1A1CHRM2CHRM1CHRM3HTT
SCHEMBL7831223 0.83 IDO1 (0.55) ALDH1A1CHRM2CHRM1CHRM3IDO1
SCHEMBL5205282 0.82 CA12 (0.49) ALDH1A1L3MBTL1KDM4ECYP3A4CYP2D6
SCHEMBL4949334 0.81 KDM4E (0.43) ALDH1A1CHRM2CHRM1CHRM3HTT
SCHEMBL30753811 0.81 TAAR1 (0.50) ALDH1A1CHRM2CHRM1CHRM3IDO1
SCHEMBL587268 0.81 ATP4A (0.48) ALDH1A1CHRM2CHRM1CHRM3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125736-A1 SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS Leo Pharma A/S (DK) 2009-12-02 EP claimed
WO-2008077404-A1 SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS LEO PHARMA A/S (DK) 2008-07-03 WO claimed
EP-1896492-A2 PLATINUM COMPLEXES WITH MONONITRILE-CONTAINING LIGANDS BIONUMERIK PHARMACEUTICALS, INC. (US) 2008-03-12 EP claimed
US-20070173485-A1 Amminecyclohexanecarbonitriledichloroplatinum; platinum is capable of rapidly undergoing chelation with the Guanine or Adenine base of a DNA oligonucleotide at the 7 position; readily taken up by tumor cells JUNIPER NETWORKS, INC. 2007-07-26 US claimed
US-7238823-B2 Platinum complexes with mononitrile-containing ligands BIONUMERIK PHARMACEUTICALS, INC. (US) 2007-07-03 US claimed
WO-2007005056-A2 PLATINUM COMPLEXES WITH MONONITRILE-CONTAINING LIGANDS BIONUMERIK PHARMACEUTICALS, INC. (US) 2007-01-11 WO claimed
US-20070004798-A1 Platinum complexes with mononitrile-containing ligands BIONUMERIK PHARMACEUTICALS, INC. 2007-01-04 US claimed
EP-4704846-A2 NOVEL ERGOLINES AND METHODS OF TREATING MOOD DISORDERS Gilgamesh Pharmaceuticals, Inc. (US) 2026-03-11 EP disclosed
EP-4608829-A2 NOVEL ERGOLINES AND METHODS OF TREATING MOOD DISORDERS Gilgamesh Pharmaceuticals, Inc. (US) 2025-09-03 EP disclosed
CN-119707776-A Indole compound, pharmaceutical composition, preparation method and application thereof 山东绿叶制药有限公司 2025-03-28 CN disclosed
US-20250084055-A1 DIHYDROQUINOLINONES FOR MEDICAL TREATMENT C4 THERAPEUTICS, INC. (US) 2025-03-13 US disclosed
WO-2025014719-A2 TROPANE COMPOUNDS FOR TREATING BRAIN DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-16 WO disclosed
CN-119144141-A Halogen-free flame-retardant TPU cable material and preparation method thereof 无锡市优艺新材料科技有限公司 2024-12-17 CN disclosed
EP-0730452-A4 HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS HOECHST ROUSSEL PHARMA (US) 1997-03-19 EP disclosed
EP-0730452-A1 HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS HOECHST MARION ROUSSEL, Inc. (US) 1996-09-11 EP disclosed
WO-1993020099-A2 CCK AND/OR GASTRIN RECEPTOR LIGANDS FERRING B.V. (NL) 1993-10-14 WO disclosed
EP-0080419-B1 8-HALOALKYL-4H-(1)-BENZOPYRAN-4-ONES AND PREPARATION PROCESSES LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1990-01-24 EP disclosed
EP-0109679-B1 PROCESS FOR THE SIMULTANEOUS PRODUCTION OF PHENYLACETATE ESTERS AND PHENYLACETALDEHYDES DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-08-14 EP disclosed
EP-0109679-A1 Process for the simultaneous production of phenylacetate esters and phenylacetaldehydes DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-05-30 EP disclosed
EP-0080419-A2 8-Haloalkyl-4H-(1)-benzopyran-4-ones and preparation processes LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1983-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004798-A1 Platinum complexes with mononitrile-containing ligands LIG4, RNMT, LIG1 ALDH1A1 658/4885CHRM2 3745/4885CHRM1 2340/4885
US-20250084055-A1 DIHYDROQUINOLINONES FOR MEDICAL TREATMENT CRBN, RBX1, ADRM1 ALDH1A1 2816/4885CHRM2 4337/4885CHRM1 4336/4885
US-20070173485-A1 Amminecyclohexanecarbonitriledichloroplatinum; platinum is capable of rapidly undergoing chelation with the Guanine or Adenine base of a DNA oligonucleotide at the 7 position; readily taken up by tumor cells RNMT, NSUN2, NUDT1 ALDH1A1 952/4885CHRM2 2623/4885CHRM1 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.