SCHEMBL2514397

SCHEMBL2514397

CCCCCCCC/C=C\CCCCCCCC(=O)Oc1cc(C=Cc2ccc(O)cc2)cc(OC(=O)CCCCCCC/C=C\CCCCCCCC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB11 A5LHX3 3/20 0.50
PSMA7 O14818 3/20 0.50
PSMB1 P20618 3/20 0.50
PSMA1 P25786 3/20 0.50
PSMA2 P25787 3/20 0.50
PSMA3 P25788 3/20 0.50
PSMA4 P25789 3/20 0.50
PSMB8 P28062 3/20 0.50
PSMB9 P28065 3/20 0.50
PSMA5 P28066 3/20 0.50
PSMB4 P28070 3/20 0.50
PSMB6 P28072 3/20 0.50
PSMB5 P28074 3/20 0.50
PSMB10 P40306 3/20 0.50
PSMB3 P49720 3/20 0.50
PSMB2 P49721 3/20 0.50
PSMA6 P60900 3/20 0.50
PSMA8 Q8TAA3 3/20 0.50
PSMB7 Q99436 3/20 0.50
ELANE P08246 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4097267 1.00 PSMB11 (0.50) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL2518028 0.98 PSMB11 (0.48) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL2519715 0.97 PSMB11 (0.49) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL4092190 0.97 PSMB11 (0.49) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL2513369 0.94 PSMB11 (0.47) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL4096611 0.94 MAPT (0.51) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL4099548 0.94 TTR (0.50) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL4101923 0.94 TTR (0.50) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL2515023 0.94 TTR (0.50) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL2521977 0.94 TTR (0.50) MEN1MAPTKMT2AGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 US disclosed
US-9782335-B2 Malic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2017-10-10 US disclosed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 US disclosed
EP-2445511-B1 SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS ELC MAN LLC (US) 2016-09-07 EP disclosed
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-08-11 US disclosed
US-9358194-B2 Succinic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2016-06-07 US disclosed
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 US disclosed
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-02-11 US disclosed
US-9180316-B2 Butyric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-11-10 US disclosed
US-9162083-B2 Linoleic and Linolenic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-10-20 US disclosed
US-8084496-B2 Resveratrol ferulate compounds and compositions ELC MANAGEMENT LLC (US) 2011-12-27 US disclosed
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2011-10-13 US disclosed
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions MAES DANIEL H 2010-08-26 US disclosed
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2010-04-01 US disclosed
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN ELC MANAGEMENT LLC 2009-02-19 US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives RB1, SIRT1, EP300 PSMB11 1827/4885PSMA7 2122/4885PSMB1 1284/4885
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone SQLE, SMURF1, PIK3R1 PSMB11 1262/4885PSMA7 1413/4885PSMB1 1011/4885
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions FER, FOLR1, FOLR2 PSMB11 2163/4885PSMA7 1622/4885PSMB1 1925/4885
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN CUTA, ERCC1, OGG1 PSMB11 3484/4885PSMA7 4322/4885PSMB1 2895/4885
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 PSMB11 3484/4885PSMA7 4322/4885PSMB1 2895/4885
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions CUTA, SUV39H1, RARA PSMB11 2453/4885PSMA7 2004/4885PSMB1 2307/4885
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 PSMB11 1301/4885PSMA7 1207/4885PSMB1 1230/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA PSMB11 2552/4885PSMA7 2764/4885PSMB1 2460/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA PSMB11 3729/4885PSMA7 3567/4885PSMB1 3457/4885
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 PSMB11 3484/4885PSMA7 4322/4885PSMB1 2895/4885
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ME1, ME2, ME3 PSMB11 3100/4885PSMA7 2592/4885PSMB1 3604/4885
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions SUCNR1, SIRT1, SUCLA2 PSMB11 3114/4885PSMA7 2994/4885PSMB1 3506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.