Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Congo Red Free Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.74 |
| ▸ | APP | P05067 | 2/20 | 1.00 |
| ▸ | GLB1 | P16278 | 1/20 | 1.00 |
| ▸ | CHAT | P28329 | 1/20 | 1.00 |
| ▸ | ENPP2 | Q13822 | 1/20 | 1.00 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 1.00 |
| ▸ | CTRC | Q99895 | 1/20 | 1.00 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | SNCA | P37840 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Congo Red Free Acid SCHEMBL202229 | 1.00 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL29395841 | 1.00 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL29366109 | 1.00 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL326084 | 0.97 | APP (0.95) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL326085 | 0.97 | APP (0.95) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988500 | 0.94 | APP (0.88) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988686 | 0.92 | APP (0.85) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL20553442 | 0.91 | APP (0.84) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988379 | 0.90 | APP (0.80) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988623 | 0.90 | APP (0.81) | APPGLB1CHATENPP2PHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 32894 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117654641-B | Cellulose-based composite bead for activating peroxymonosulfate degradation dye and preparation method thereof | GUILIN UNIVERSITY OF TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122081063-A | Concentration, temperature and illumination multi-factor cell culture chip device and method | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081253-A | Laccase mutant and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076471-A | Metal basic salt mineralized membrane, preparation method thereof and application of metal basic salt mineralized membrane serving as heterogeneous catalyst in treatment of organic wastewater | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076396-A | Multifunctional aerogel film based on charge demulsification, preparation method and application | — | 2026-05-26 | — | — | CN | claimed |
| WO-2026105201-A1 | SECONDARY BATTERY | ＮＴＴ株式会社 | 2026-05-21 | — | — | WO | claimed |
| EP-4427033-B1 | METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES | PAIA BIOTECH GMBH (DE) | 2026-05-20 | — | — | EP | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122059518-A | Application of lignin-based flocculant in treatment of wastewater containing anionic dye | 中国人民大学 | 2026-05-19 | — | — | CN | claimed |
| CN-121869097-B | Molecular sieve self-assembled light response film and preparation method and application thereof | 天津工业大学 | 2026-05-15 | — | — | CN | claimed |
| EP-0003583-B1 | COMPOSITIONS FOR CYTOCHEMICAL INVESTIGATION, THEIR USE AND METHOD FOR THE DETECTION OF STEROID HORMONE RECEPTORS IN HUMAN TISSUES | Lee, Sin Hang (US) | 1981-12-02 | — | — | EP | claimed |
| US-4298569-A | Steam-formaldehyde sterilization indicator | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-11-03 | — | — | US | claimed |
| US-4215102-A | Cytochemical agents and methods for the detection of steroid hormone receptors in human tissues | LEE SIN H | 1980-07-29 | — | — | US | claimed |
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | claimed |
| EP-0003583-A1 | Compositions for cytochemical investigation, their use and method for the detection of steroid hormone receptors in human tissues | Lee, Sin Hang (US) | 1979-08-22 | — | — | EP | claimed |
| US-4162207-A | TO SULFUR TRIOXIDE BY OXIDATION IN PRESENCE OF PHOTOSENSITIZER | BOYER STEPHEN K | 1979-07-24 | — | — | US | claimed |
| US-4116634-A | Void, flaw, and crack indicator for epoxy bonds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1978-09-26 | — | — | US | claimed |
| US-4104204-A | Photosensitization of oxygen to the singlet excited state using ion exchange resin to which is attached a dye and photooxidative waste water treatment | TEMPLE UNIVERSITY (US) | 1978-08-01 | — | — | US | claimed |
| US-4025164-A | Liquid crystal display device for colored display of information with a selective polarizer | BBC BROWN BOVERI & COMPANY LIMITED (CH) | 1977-05-24 | — | — | US | claimed |
| US-3972893-A | Method for preparing cobalt phthalocyanine complex salts | NIPPON CHEMICAL WORKS CO., LTD. (JA) | 1976-08-03 | — | — | US | claimed |