Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.64 |
| ▸ | APP | P05067 | 2/20 | 0.84 |
| ▸ | GLB1 | P16278 | 1/20 | 0.84 |
| ▸ | CHAT | P28329 | 1/20 | 0.84 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.84 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.84 |
| ▸ | CTRC | Q99895 | 1/20 | 0.84 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Congo Red Free Acid SCHEMBL29395841 | 0.91 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL29366109 | 0.91 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL202229 | 0.91 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL25635 | 0.91 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL326084 | 0.89 | APP (0.95) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL326085 | 0.89 | APP (0.95) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988686 | 0.86 | APP (0.85) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988500 | 0.86 | APP (0.88) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988820 | 0.84 | APP (0.81) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988672 | 0.84 | SLC7A11 (1.00) | APPGLB1CHATENPP2PHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10126304-B2 | Binding domain mapping | George Mason Research Foundation, Inc. (US) | 2018-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10126304-B2 | Binding domain mapping | SNRPE, HSPBP1, CNBP | THRB 3094/4885APP 3935/4885GLB1 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.