Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Congo Red Free Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.74 |
| ▸ | APP | P05067 | 2/20 | 1.00 |
| ▸ | GLB1 | P16278 | 1/20 | 1.00 |
| ▸ | CHAT | P28329 | 1/20 | 1.00 |
| ▸ | ENPP2 | Q13822 | 1/20 | 1.00 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 1.00 |
| ▸ | CTRC | Q99895 | 1/20 | 1.00 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | SNCA | P37840 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Congo Red Free Acid SCHEMBL25635 | 1.00 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL29395841 | 1.00 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL29366109 | 1.00 | APP (1.00) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL326084 | 0.97 | APP (0.95) | APPGLB1CHATENPP2PHLPP2 | |
| Congo Red Free Acid SCHEMBL326085 | 0.97 | APP (0.95) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988500 | 0.94 | APP (0.88) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988686 | 0.92 | APP (0.85) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL20553442 | 0.91 | APP (0.84) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988379 | 0.90 | APP (0.80) | APPGLB1CHATENPP2PHLPP2 | |
| SCHEMBL14988623 | 0.90 | APP (0.81) | APPGLB1CHATENPP2PHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 691 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333374-A1 | ORGANIC AMMONIUM SALTS WITH TRACEABILITY AND DETERGENT DISPERSANT PROPERTIES TO LIQUID FUELS AND PROCESSES FOR THEIR SYNTHESIS | MEXICANO INST PETROL (MX) | 2025-10-30 | — | — | US | claimed |
| US-12130267-B2 | Analyzing method for azo compound | SHIMADZU CORPORATION (JP) | 2024-10-29 | — | — | US | claimed |
| CN-118698169-A | Method for simultaneously measuring 5 harmful dyes such as disperse red 60 and the like in textile | 湖州检验检疫综合技术服务中心 | 2024-09-27 | — | — | CN | claimed |
| CN-115628961-B | Microsporidian fluorescent staining marking method and application | 山东大学 | 2024-09-10 | — | — | CN | claimed |
| US-12071446-B1 | Metal organic frameworks containing face-centered cubic topology supported by carbon nanotubes | King Faisal University (SA) | 2024-08-27 | — | — | US | claimed |
| US-20240190812-A1 | ORGANIC AMMONIUM SALTS WITH TRACEABILITY AND DETERGENT DISPERSANT PROPERTIES TO LIQUID FUELS AND PROCESSES FOR THEIR SYNTHESIS | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2024-06-13 | — | — | US | claimed |
| CN-116754687-A | Liquid chromatography-tandem mass spectrometry combined detection method for forbidden dye in printing and dyeing wastewater | 绍兴海关综合技术服务中心 | 2023-09-15 | — | — | CN | claimed |
| CN-115628961-A | Microsporidium fluorescent staining labeling method and application | 山东大学 | 2023-01-20 | — | — | CN | claimed |
| CN-114371244-A | Quality control method for banned azo dye detection of textile | 中纺标检验认证股份有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-109632988-B | Method for detecting content of disperse dye | 广州广电计量检测股份有限公司 | 2022-02-01 | — | — | CN | claimed |
| US-6739779-B1 | Fabric repair coloring device and method of using | DEEDS SUZANNE M (US) | 2004-05-25 | — | — | US | claimed |
| US-20030035211-A1 | Light-polarizing film | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-02-20 | — | — | US | claimed |
| US-6522468-B2 | Comprising direct orange or red dichroic dye; liquid crystal displays with bright and natural color tones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-02-18 | — | — | US | claimed |
| US-6395303-B1 | Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose | EDWARD MENDELL CO., INC. | 2002-05-28 | — | — | US | claimed |
| US-20010040652-A1 | LIGHT-POLARIZING FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-15 | — | — | US | claimed |
| EP-1037072-A2 | Light-polarizing film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-20 | — | — | EP | claimed |
| US-6106865-A | MIXTURE OF MICROCRYSTALLINE CELLULOSE, COMPRESSIBILITY, SILICA AND SURFACTANTS | EDWARD MENDELL CO., INC. (US) | 2000-08-22 | — | — | US | claimed |
| US-5602234-A | MIXTURE OF ANTIBODY, ALBUMIN AND AZO DYE | DOJIN IYAKU-KAKO CO., LTD. (JP) | 1997-02-11 | — | — | US | claimed |
| US-5569571-A | COATING, DRYING, EXPOSING AND DEVELOPING A PHOTORESIST ON INSIDE OF SUBSTRATE, DRYING, COATING A DYE, DRYING AGAIN, COATING GRAPHITE LAYER, AND ETCHING; BLACK MATRIX IS USED FOR MAKING COLOR PICTURE TUBE OR COLOR DISPLAY TUBE | SAMSUNG DISPLAY DEVICES CO., LTD. (KR) | 1996-10-29 | — | — | US | claimed |
| US-5071906-A | POLARIZING FILM AND PROCESS FOR THE PRODUCTION OF THE SAME | UNITIKA LTD. (JP) | 1991-12-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190812-A1 | ORGANIC AMMONIUM SALTS WITH TRACEABILITY AND DETERGENT DISPERSANT PROPERTIES TO LIQUID FUELS AND PROCESSES FOR THEIR SYNTHESIS | COPE, RAB5IF, COG4 | THRB 4155/4885APP 2361/4885GLB1 785/4885 |
| US-20250333374-A1 | ORGANIC AMMONIUM SALTS WITH TRACEABILITY AND DETERGENT DISPERSANT PROPERTIES TO LIQUID FUELS AND PROCESSES FOR THEIR SYNTHESIS | COPE, RAB5IF, COG4 | THRB 4155/4885APP 2361/4885GLB1 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.