SCHEMBL257904

SCHEMBL257904

CC1(C)OB(c2ccc(O)cc2F)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPL P06858 4/20 0.40
LIPG Q9Y5X9 4/20 0.40
ESR1 P03372 8/20 0.38
ESR2 Q92731 6/20 0.36
JAK2 O60674 2/20 0.34
BTK Q06187 2/20 0.34
ROCK1 Q13464 1/20 0.33
CXCR2 P25025 1/20 0.32
F11 P03951 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MIF P14174 1/20 0.31
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29748917 1.00 LPL (0.40) LPLLIPGESR1ESR2JAK2
SCHEMBL12496566 0.86 LPL (0.40) LPLLIPGESR1ESR2JAK2
SCHEMBL897058 0.81 LPL (0.50) LPLLIPGJAK2BTKROCK1
SCHEMBL29424567 0.81 LPL (0.50) LPLLIPGJAK2BTKROCK1
SCHEMBL5477046 0.81 LPL (0.35) LPLLIPGF11CA1CA2
SCHEMBL21042445 0.81 LIPG (0.50) LPLLIPGJAK2BTKROCK1
SCHEMBL37395635 0.80 LPL (0.41) LPLLIPGJAK2BTKROCK1
SCHEMBL29978910 0.80 ESR2 (0.39) LPLLIPGESR1ESR2F11
SCHEMBL257840 0.80 ESR2 (0.39) LPLLIPGESR1ESR2F11
SCHEMBL6120636 0.80 LPL (0.41) LPLLIPGJAK2BTKROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4344702-B1 PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2026-01-28 EP disclosed
US-20260001864-A1 COMPOUND CONTAINING SULFAMIDE STRUCTURE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITION AND APPLICATION NANJING SHUOHUI PHARMATECHNOLOGY CO., LTD (CN) 2026-01-01 US disclosed
US-12473289-B2 Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use AMGEN INC. (US) 2025-11-18 US disclosed
US-20250115613-A1 DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) 2025-04-10 US disclosed
US-20250059176-A1 SUBSTITUTED NICOTINIMIDE INHIBITORS OF BTK FOR TREATING CANCER GUANGZHOU INNOCARE PHARMA TECH CO LTD (CN) 2025-02-20 US disclosed
US-12162873-B2 Substituted nicotinimide inhibitors of BTK for treating cancer GUANGZHOU INNOCARE PHARMA TECH CO., LTD. (CN) 2024-12-10 US disclosed
EP-4464700-A1 DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) 2024-11-20 EP disclosed
US-20240360082-A1 SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS NOVARTIS AG (CH) 2024-10-31 US disclosed
WO-2024208315-A1 AROMATIC HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 中国医药研究开发中心有限公司 2024-10-10 WO disclosed
EP-4373809-A1 SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS Novartis AG (CH) 2024-05-29 EP disclosed
US-7947663-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2011-05-24 US disclosed
US-7947663-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2011-05-24 US disclosed
WO-2011050893-A1 POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-05-05 WO disclosed
WO-2011050893-A1 POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-05-05 WO disclosed
WO-2010069504-A1 (3-OXO)PYRIDIN-4-YLUREA DERIVATIVES AS PDE4 INHIBITORS ALMIRALL, S.A. (ES) 2010-06-24 WO disclosed
EP-2196465-A1 (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors Almirall, S.A. (ES) 2010-06-16 EP disclosed
EP-2196465-A1 (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors Almirall, S.A. (ES) 2010-06-16 EP disclosed
US-20090099131-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY DISCOVERY, INC. (US) 2009-04-16 US disclosed
US-20090099131-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY DISCOVERY, INC. (US) 2009-04-16 US disclosed
WO-2008063300-A2 BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. (US) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115613-A1 DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR SRC, DSTYK, TUBB1 LPL 4837/4885LIPG 4794/4885ESR1 3726/4885
US-20090099131-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 LPL 180/4885LIPG 272/4885ESR1 4454/4885
US-20250059176-A1 SUBSTITUTED NICOTINIMIDE INHIBITORS OF BTK FOR TREATING CANCER BTK, SYK, LYN LPL 3698/4885LIPG 3306/4885ESR1 3077/4885
US-20260001864-A1 COMPOUND CONTAINING SULFAMIDE STRUCTURE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITION AND APPLICATION SLC10A2, SLC6A11, ABCB11 LPL 2987/4885LIPG 4436/4885ESR1 3064/4885
US-12473289-B2 Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use SCD5, SCD, FADS2 LPL 152/4885LIPG 205/4885ESR1 1861/4885
US-12162873-B2 Substituted nicotinimide inhibitors of BTK for treating cancer BTK, SYK, LYN LPL 3698/4885LIPG 3306/4885ESR1 3077/4885
US-20240360082-A1 SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS PNPO, PDXK, PLPBP LPL 1994/4885LIPG 2161/4885ESR1 4464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.