Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31233926 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL774378 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL774781 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL775555 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL19536211 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL774379 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL23870571 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL774780 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL8165550 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1GAAMAPT | |
| SCHEMBL19514134 | 0.98 | FAAH (0.44) | ALDH1A1POLBMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11833129-B2 | Thiophene compound for treatment of exfoliating glaucoma | AVOSCIENCE, LLC (US) | 2023-12-05 | — | — | US | disclosed |
| US-11833129-B2 | Thiophene compound for treatment of exfoliating glaucoma | AVOSCIENCE, LLC (US) | 2023-12-05 | — | — | US | disclosed |
| US-11602518-B2 | Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis | AVOSCIENCE, LLC (US) | 2023-03-14 | — | — | US | disclosed |
| US-11058663-B2 | Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders | AVOSCIENCE, LLC (US) | 2021-07-13 | — | — | US | disclosed |
| US-20210137876-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS | AVOSCIENCE, LLC (US) | 2021-05-13 | — | — | US | disclosed |
| US-20210106551-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR USE IN THE TREATMENT OF ATROPHIC VAGINITIS | AVOSCIENCE, LLC (US) | 2021-04-15 | — | — | US | disclosed |
| US-10905673-B2 | Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis | AVOSCIENCE, LLC (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200237709-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS | AVOSCIENCE, LLC (US) | 2020-07-30 | — | — | US | disclosed |
| US-20190274994-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR USE IN THE TREATMENT OF ATROPHIC VAGINITIS | AVOSCIENCE, LLC (US) | 2019-09-12 | — | — | US | disclosed |
| US-20180050013-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS | AVOSCIENCE, LLC (US) | 2018-02-22 | — | — | US | disclosed |
| US-7589121-B2 | Use of furan alkyls for preparing a drug for treating obesity and cosmetically treating overweight | LABORATOIRES EXPANSCIENCE (FR) | 2009-09-15 | — | — | US | disclosed |
| US-7589121-B2 | Use of furan alkyls for preparing a drug for treating obesity and cosmetically treating overweight | LABORATOIRES EXPANSCIENCE (FR) | 2009-09-15 | — | — | US | disclosed |
| US-20080219937-A1 | purified furanic fraction of unsaponifiable of avocado, used for reducing, eliminating or preventing pigment spots, on the skin of a person | LABORATOIRES EXPANSCIENCE (FR) | 2008-09-11 | — | — | US | disclosed |
| US-20080219937-A1 | purified furanic fraction of unsaponifiable of avocado, used for reducing, eliminating or preventing pigment spots, on the skin of a person | LABORATOIRES EXPANSCIENCE (FR) | 2008-09-11 | — | — | US | disclosed |
| US-20080081837-A1 | Reducing glucose blood concentration and increasing tolerance with unsaponifiable avocado extract | LABORATOIRES EXPANSCIENCE | 2008-04-03 | — | — | US | disclosed |
| US-20080081837-A1 | Reducing glucose blood concentration and increasing tolerance with unsaponifiable avocado extract | LABORATOIRES EXPANSCIENCE | 2008-04-03 | — | — | US | disclosed |
| US-20070281994-A1 | Use Of Furan Alkyls For A Cellulite Cosmetic Treatment | LABORATOIRES EXPANSCIENCE | 2007-12-06 | — | — | US | disclosed |
| US-20070281994-A1 | Use Of Furan Alkyls For A Cellulite Cosmetic Treatment | LABORATOIRES EXPANSCIENCE | 2007-12-06 | — | — | US | disclosed |
| US-20070238777-A1 | Use of Furan Alkyls for Preparing a Drug for Treating Obesity and Cosmetically Treating Overweight | LABORATOIRES EXPANSCIENCE | 2007-10-11 | — | — | US | disclosed |
| US-20070238777-A1 | Use of Furan Alkyls for Preparing a Drug for Treating Obesity and Cosmetically Treating Overweight | LABORATOIRES EXPANSCIENCE | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238777-A1 | Use of Furan Alkyls for Preparing a Drug for Treating Obesity and Cosmetically Treating Overweight | ACSL5, FASN, MC5R | ALDH1A1 129/4885POLB 3274/4885MEN1 1535/4885 |
| US-10905673-B2 | Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis | LPXN, PGR, CYP19A1 | ALDH1A1 1266/4885POLB 1439/4885MEN1 4491/4885 |
| US-20210137876-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS | FAH, PHOSPHO1, FAP | ALDH1A1 354/4885POLB 3374/4885MEN1 1122/4885 |
| US-20080219937-A1 | purified furanic fraction of unsaponifiable of avocado, used for reducing, eliminating or preventing pigment spots, on the skin of a person | TYR, APEH, ALAD | ALDH1A1 64/4885POLB 2417/4885MEN1 2414/4885 |
| US-20070281994-A1 | Use Of Furan Alkyls For A Cellulite Cosmetic Treatment | ACSL5, FASN, CUTA | ALDH1A1 747/4885POLB 3118/4885MEN1 2320/4885 |
| US-20200237709-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS | FAH, PHOSPHO1, FAP | ALDH1A1 354/4885POLB 3374/4885MEN1 1122/4885 |
| US-20190274994-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR USE IN THE TREATMENT OF ATROPHIC VAGINITIS | LPXN, PGR, CYP19A1 | ALDH1A1 1266/4885POLB 1439/4885MEN1 4491/4885 |
| US-11058663-B2 | Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders | FAH, PHOSPHO1, FAP | ALDH1A1 354/4885POLB 3374/4885MEN1 1122/4885 |
| US-20180050013-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS | FAH, PHOSPHO1, FAP | ALDH1A1 354/4885POLB 3374/4885MEN1 1122/4885 |
| US-20210106551-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR USE IN THE TREATMENT OF ATROPHIC VAGINITIS | LPXN, PGR, CYP19A1 | ALDH1A1 1266/4885POLB 1439/4885MEN1 4491/4885 |
| US-20080081837-A1 | Reducing glucose blood concentration and increasing tolerance with unsaponifiable avocado extract | FOS, IRS1, GPR119 | ALDH1A1 1153/4885POLB 3488/4885MEN1 455/4885 |
| US-11833129-B2 | Thiophene compound for treatment of exfoliating glaucoma | TYMP, TDP1, TDP2 | ALDH1A1 895/4885POLB 2304/4885MEN1 1722/4885 |
| US-11602518-B2 | Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis | LPXN, PGR, CYP19A1 | ALDH1A1 1266/4885POLB 1439/4885MEN1 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.