SCHEMBL2620533

SCHEMBL2620533

Cc1c(Cc2ccc(O)c(N)c2C)ccc(O)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AMY1A P0DUB6 1/20 0.39
▸ HSD17B10 Q99714 3/20 0.37
▸ GAA P10253 3/20 0.37
▸ GFER P55789 1/20 0.37
▸ ALDH1A1 P00352 4/20 0.37
▸ ALOX15 P16050 3/20 0.37
▸ PDE10A Q9Y233 1/20 0.37
▸ MAPT P10636 3/20 0.36
▸ TYR P14679 1/20 0.36
▸ HSPA5 P11021 2/20 0.36
▸ HTT P42858 2/20 0.35
▸ CASP1 P29466 2/20 0.35
▸ HIF1A Q16665 2/20 0.35
▸ ESR1 P03372 2/20 0.35
▸ ESR2 Q92731 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ SLC22A1 O15245 1/20 0.35
▸ USP2 O75604 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4063406 0.78 TYR (0.44) AMY1AGAAALDH1A1ALOX15MAPT
SCHEMBL4815999 0.78 ALDH1A1 (0.44) HSD17B10GAAGFERALDH1A1ALOX15
SCHEMBL23919938 0.76 AMY1A (0.47) AMY1AGAAALOX15MAPTTYR
SCHEMBL1259716 0.76 POLB (0.54) HSD17B10GAAALDH1A1ALOX15MAPT
SCHEMBL8977704 0.74 GABRA1 (0.36) HSD17B10GAAALDH1A1ALOX15MAPT
SCHEMBL16429287 0.73 POLB (0.56) HSD17B10GAAGFERALDH1A1ALOX15
SCHEMBL1568810 0.73 ALDH1A1 (0.52) HSD17B10GAAGFERALDH1A1ALOX15
SCHEMBL118836 0.73 TSHR (0.46) HSD17B10GAAGFERALDH1A1ALOX15
SCHEMBL9838984 0.73 KDM4E (0.51) HSD17B10ALDH1A1ALOX15MAPTCASP1
SCHEMBL31244461 0.71 TYR (0.57) AMY1AHSD17B10ALOX15MAPTTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530119-B2 Positive photosensitive resin composition, cured film, protective film, interlayer insulating film, and semiconductor device and display element using the same SUMITOMO BAKELITE CO., LTD. (JP) 2013-09-10 — — US disclosed
US-8530119-B2 Positive photosensitive resin composition, cured film, protective film, interlayer insulating film, and semiconductor device and display element using the same SUMITOMO BAKELITE CO., LTD. (JP) 2013-09-10 — — US disclosed
US-8269358-B2 Bis(aminophenol) derivative, process for producing same, polyamide resin, positive photosensitive resin composition, protective film, interlayer dielectric film, semiconductor device, and display element SUMITOMO BAKELITE COMPANY LIMITED (JP) 2012-09-18 — — US disclosed
US-20120100484-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, PROTECTIVE FILM, INTERLAYER INSULATING FILM, AND SEMICONDUCTOR DEVICE AND DISPLAY ELEMENT USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2012-04-26 — — US disclosed
US-20120100484-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, PROTECTIVE FILM, INTERLAYER INSULATING FILM, AND SEMICONDUCTOR DEVICE AND DISPLAY ELEMENT USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2012-04-26 — — US disclosed
US-20100044888-A1 BIS(AMINOPHENOL) DERIVATIVE, PROCESS FOR PRODUCING SAME, POLYAMIDE RESIN, POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PROTECTIVE FILM, INTERLAYER DIELECTRIC FILM, SEMICONDUCTOR DEVICE, AND DISPLAY ELEMENT SUMITOMO BAKELITE COMPANY LIMITED (JP) 2010-02-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100044888-A1 BIS(AMINOPHENOL) DERIVATIVE, PROCESS FOR PRODUCING SAME, POLYAMIDE RESIN, POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PROTECTIVE FILM, INTERLAYER DIELECTRIC FILM, SEMICONDUCTOR DEVICE, AND DISPLAY ELEMENT RARA, AASDHPPT, GABRP AMY1A 4163/4885HSD17B10 4338/4885GAA 3326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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