SCHEMBL26652440

SCHEMBL26652440

Cc1ccc(-c2ccc(C)c(-c3cc(C#N)cc(C(F)(F)F)c3)c2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 3/20 0.46
▸ RXRG P48443 2/20 0.46
▸ KIF11 P52732 2/20 0.41
▸ RXRB P28702 2/20 0.40
▸ XDH P47989 1/20 0.39
▸ AR P10275 3/20 0.38
▸ PTGDR2 Q9Y5Y4 1/20 0.37
▸ GPBAR1 Q8TDU6 1/20 0.37
▸ PSEN1 P49768 1/20 0.37
▸ PSEN2 P49810 1/20 0.37
▸ APH1B Q8WW43 1/20 0.37
▸ NCSTN Q92542 1/20 0.37
▸ APH1A Q96BI3 1/20 0.37
▸ PSENEN Q9NZ42 1/20 0.37
▸ APP P05067 1/20 0.37
▸ BACE1 P56817 1/20 0.37
▸ PGR P06401 1/20 0.35
▸ CYP11B1 P15538 1/20 0.35
▸ CYP11B2 P19099 1/20 0.35
▸ PTPN5 P54829 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26555707 0.85 CTSK (0.40) ARPGRCYP11B1CYP11B2CTSK
SCHEMBL26532922 0.85 RXRB (0.51) RXRARXRGKIF11RXRBPSEN1
SCHEMBL26017262 0.81 RXRA (0.44) RXRARXRGKIF11RXRBGPBAR1
SCHEMBL26555703 0.77 CYP11B2 (0.44) KIF11CYP11B1CYP11B2CTSK
SCHEMBL26532921 0.77 KIF11 (0.45) RXRARXRGKIF11RXRBAPP
SCHEMBL26555715 0.75 KIF11 (0.46) KIF11ARPTGDR2PGRCYP11B1
SCHEMBL27479450 0.73 RXRA (0.59) RXRARXRGKIF11RXRBXDH
SCHEMBL18001587 0.72 RXRA (0.55) RXRARXRGKIF11RXRBXDH
SCHEMBL26532565 0.72 RXRA (0.41) RXRARXRGKIF11RXRBAR
SCHEMBL26375444 0.70 NOTUM (0.46) RXRARXRGKIF11RXRBPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 RXRA 361/4885RXRG 641/4885KIF11 3143/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR RXRA 82/4885RXRG 153/4885KIF11 3131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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