Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 5/20 | 0.57 |
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.57 |
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.57 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716108 | 0.89 | CA12 (0.56) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28498866 | 0.86 | CA12 (0.54) | CA12CA1CA2CA9LMNA | |
| SCHEMBL10928532 | 0.86 | CA12 (0.59) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8746483 | 0.86 | CA12 (0.59) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11730543 | 0.84 | CA12 (0.60) | CA12CA1CA2CA9LMNA | |
| SCHEMBL15268433 | 0.84 | CA12 (0.55) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9624630 | 0.83 | CA12 (0.50) | CA12CA1CA2CA9LMNA | |
| SCHEMBL3115297 | 0.82 | LMNA (0.77) | CA12CA1CA2CA9LMNA | |
| SCHEMBL30139086 | 0.82 | LMNA (0.77) | CA12CA1CA2CA9LMNA | |
| SCHEMBL757098 | 0.82 | LMNA (0.77) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976415-B1 | COLOUR PROTECTING DETERGENT COMPOPOSITION COMPRISING AN OPTICAL BRIGHTENER | HENKEL AG & CO KGAA (DE) | 2018-10-17 | — | — | EP | claimed |
| EP-2976415-A1 | COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER | Henkel AG&Co. KGAA (DE) | 2016-01-27 | — | — | EP | claimed |
| WO-2014146985-A1 | COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER | HENKEL AG & CO. KGAA (DE) | 2014-09-25 | — | — | WO | claimed |
| EP-2176392-B1 | COLOR-SAFE DETERGENT OR CLEANING AGENT HAVING OPTICAL BRIGHTENER | HENKEL AG & CO KGAA (DE) | 2013-10-23 | — | — | EP | claimed |
| EP-4652254-A1 | DETERGENT HAVING IMPROVED WASHING/CLEANING PERFORMANCE | Henkel AG & Co. KGaA (DE) | 2025-11-26 | — | — | EP | disclosed |
| WO-2025124777-A1 | DETERGENT OR CLEANING AGENT MOLDED BODIES | HENKEL AG & CO. KGAA (DE) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025124794-A1 | DETERGENT OR CLEANING AGENT MOLDED BODIES | HENKEL AG & CO. KGAA (DE) | 2025-06-19 | — | — | WO | disclosed |
| EP-4504884-A1 | HAIR REMOVAL BY MEANS OF DETERGENT/DETERGENT ADDITIVES CONTAINING ENZYMES | Henkel AG & Co. KGaA (DE) | 2025-02-12 | — | — | EP | disclosed |
| EP-3753971-B1 | POLYMERS FOR THE TREATMENT OF SURFACES | HENKEL AG & CO KGAA (DE) | 2024-11-27 | — | — | EP | disclosed |
| EP-3749738-B1 | VISCOELASTIC, SOLID SURFACTANT COMPOSITION | HENKEL AG & CO KGAA (DE) | 2024-08-14 | — | — | EP | disclosed |
| WO-2024153572-A1 | DETERGENT HAVING IMPROVED WASHING/CLEANING PERFORMANCE | HENKEL AG & CO. KGAA (DE) | 2024-07-25 | — | — | WO | disclosed |
| CN-113646415-B | Use of mannanases in combination with catechol derivatives | 汉高股份有限及两合公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-2976415-A1 | COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER | Henkel AG&Co. KGAA (DE) | 2016-01-27 | — | — | EP | disclosed |
| WO-2014146985-A1 | COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER | HENKEL AG & CO. KGAA (DE) | 2014-09-25 | — | — | WO | disclosed |
| EP-2176392-B1 | COLOR-SAFE DETERGENT OR CLEANING AGENT HAVING OPTICAL BRIGHTENER | HENKEL AG & CO KGAA (DE) | 2013-10-23 | — | — | EP | disclosed |
| EP-2633019-A1 | DETERGENTS WITH ANTIMICROBIAL EFFECT | Henkel AG & Co. KGaA (DE) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012055775-A1 | DETERGENTS WITH ANTIMICROBIAL EFFECT | HENKEL AG & CO. KGAA (DE) | 2012-05-03 | — | — | WO | disclosed |
| EP-2176392-A1 | COLOR-SAFE DETERGENT OR CLEANING AGENT HAVING OPTICAL BRIGHTENER | Henkel AG & Co. KGaA (DE) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009019136-A1 | COLOR-SAFE DETERGENT OR CLEANING AGENT HAVING OPTICAL BRIGHTENER | HENKEL AG & CO. KGAA (DE) | 2009-02-12 | — | — | WO | disclosed |
| US-3980669-A | Continuous process for manufacturing gamma sultones | COLGATE-PALMOLIVE COMPANY (US) | 1976-09-14 | — | — | US | disclosed |