Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.52 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.52 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.42 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673135 | 0.84 | TDP1 (0.43) | CA2CA4CES1MAPTTDP1 | |
| SCHEMBL27796051 | 0.80 | TDP1 (0.40) | CA2CA4CES1MAPTTDP1 | |
| SCHEMBL3936738 | 0.78 | CA2 (0.48) | CA2CA4CES1MAPTTDP1 | |
| SCHEMBL27552924 | 0.77 | CES1 (0.52) | CA2CA4CES1MAPTTDP1 | |
| Benzoic Acid SCHEMBL10821940 | 0.76 | TSHR (0.67) | CA2CA4CES1MEN1KMT2A | |
| Benzoic Acid SCHEMBL10821883 | 0.76 | TSHR (0.67) | CA2CA4CES1MEN1KMT2A | |
| SCHEMBL5604703 | 0.76 | CES2 (0.57) | CA2CES1MAPTTDP1CYP3A4 | |
| SCHEMBL6844400 | 0.75 | CES1 (0.50) | CA2CA4CES1MAPTTDP1 | |
| SCHEMBL1728427 | 0.75 | CES1 (0.50) | CA2CA4CES1MAPTTDP1 | |
| Benzophenone SCHEMBL28662703 | 0.74 | ALDH1A1 (0.64) | CA2CA4MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852310-A | Refining method of prednisolone sodium benzoyl sulfonate | 河南利华制药有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-111377995-B | Preparation method of prednisolone sodium benzoylsulfonate | 天津药业研究院股份有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| CN-118852310-A | Refining method of prednisolone sodium benzoyl sulfonate | 河南利华制药有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118852310-A | Refining method of prednisolone sodium benzoyl sulfonate | 河南利华制药有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118852310-A | Refining method of prednisolone sodium benzoyl sulfonate | 河南利华制药有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118724994-A | Method for synthesizing prednisolone sodium benzoyl sulfonate | 湖南玉新药业有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-118724994-A | Method for synthesizing prednisolone sodium benzoyl sulfonate | 湖南玉新药业有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-117247545-A | Azacyclic sulfonated polyarylethersulfone polymer, preparation method and application thereof | 国家电投集团氢能科技发展有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-111377995-B | Preparation method of prednisolone sodium benzoylsulfonate | 天津药业研究院股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-111377995-B | Preparation method of prednisolone sodium benzoylsulfonate | 天津药业研究院股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-111377995-B | Preparation method of prednisolone sodium benzoylsulfonate | 天津药业研究院股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113651733-A | Synthesis process and continuous separation process of sodium o-sulfonate benzaldehyde | 赤峰市恒荣化工有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-111377995-A | Preparation method of prednisolone sodium benzoylsulfonate | 天津药业研究院有限公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-1178699-C | Pharmaceutical Compsns. contg. compounds with activity for enhancement of absorption of active ingredients | — | 2004-12-08 | — | — | CN | disclosed |
| CN-1092516-C | Preparation for epidermis and process for its preparation | SANSHO SEIYAKU KK (JP) | 2002-10-16 | — | — | CN | disclosed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | disclosed |
| CN-1191492-A | Improved pharmaceutical dosage forms for controlled release prepared by combining hydrophilic and hydrophobic agents | OCULEX PHARM INC (US) | 1998-08-26 | — | — | CN | disclosed |
| CN-1106660-A | Preparation for epidermis and process for its preparation | SANSHO SEIYAKU KK (JP) | 1995-08-16 | — | — | CN | disclosed |
| CN-1106658-A | Preparation for epidermis and process for its preparation | SANSHO SEIYAKU KK (JP) | 1995-08-16 | — | — | CN | disclosed |