Sugi Predict

Sugi Predict / Compounds / SCHEMBL275646

SCHEMBL275646

SCHEMBL275646

CCOc1ccc(C(=O)Cl)cc1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PARP10 Q53GL7 1/20 0.66
▸ NPC1 O15118 2/20 0.61
▸ PLK1 P53350 1/20 0.61
▸ NQO1 P15559 1/20 0.58
▸ NPSR1 Q6W5P4 2/20 0.58
▸ PLA2G4B P0C869 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ ALDH1A1 P00352 3/20 0.56
▸ RAB9A P51151 1/20 0.56
▸ PRSS1 P07477 1/20 0.55
▸ PRSS2 P07478 1/20 0.55
▸ PRSS3 P35030 1/20 0.55
▸ HPGD P15428 3/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.53
▸ POLB P06746 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6642345 0.94 PARP10 (0.59) PARP10NPC1PLK1NQO1NPSR1
SCHEMBL7721896 0.91 TP53 (0.58) PARP10NPC1PLK1PLA2G4BKMT2A
SCHEMBL5202729 0.84 L3MBTL1 (0.64) NPC1PLK1NPSR1PLA2G4BALDH1A1
SCHEMBL162987 0.84 TP53 (0.64) PLA2G4BKMT2AALDH1A1HPGDL3MBTL1
SCHEMBL10716251 0.83 THRA (0.60) PARP10PLK1PLA2G4BALDH1A1RAB9A
Morpholine SCHEMBL7989434 0.83 HPGD (0.48) PARP10NPC1PLK1NPSR1PLA2G4B
SCHEMBL1367365 0.83 PARP10 (0.70) PARP10NPC1PLK1NQO1NPSR1
SCHEMBL845348 0.83 NPSR1 (0.79) PARP10NPC1PLK1NQO1NPSR1
SCHEMBL10954272 0.83 MAPT (0.59) PARP10PLK1ALDH1A1RAB9APRSS1
SCHEMBL9130182 0.82 GAA (0.62) NPSR1PLA2G4BALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569803-A Method for preparing high-purity estetrol 秦皇岛紫竹药业有限公司 2025-03-07 — — CN claimed
CN-117510429-A Compound containing methyl isoxazole structure, and preparation method and application thereof 中国农业大学 2024-02-06 — — CN claimed
CN-114853627-B Substituted docosahexaenoic amide ethyl benzoate derivative and preparation method and application thereof 自然资源部第三海洋研究所 2023-06-20 — — CN claimed
CN-114853627-A Substituted docosahexaenoic acid diethyl ester derivative as well as preparation method and application thereof 自然资源部第三海洋研究所 2022-08-05 — — CN claimed
US-4069252-A Process for the preparation of certain acyl cyanide compounds BAYER AKTIENGESELLSCHAFT (DT) 1978-01-17 — — US claimed
US-12570610-B2 Macromolecule-supported aminobenzazepine compounds BOLT BIOTHERAPEUTICS, INC. (US) 2026-03-10 — — US disclosed
US-20260022098-A1 BULLEYACONITINE A DERIVATIVE WITH ANALGESIC ACTIVITY, AND PREPARATION METHOD AND APPLICATION THEREOF UNIV SOUTHWEST JIAOTONG (CN) 2026-01-22 — — US disclosed
WO-2025224270-A1 NEW HETEROCYCLIC COMPOUNDS REDUCING THE TASL PROTEIN LEVEL SOLGATE GMBH (AT) 2025-10-30 — — WO disclosed
US-20250263392-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2025-08-21 — — US disclosed
US-20250248990-A1 QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE NEURODON CORPORATION 2025-08-07 — — US disclosed
CN-115626894-B Lappaconitine derivative with analgesic activity, and preparation method and application thereof 西南交通大学 2025-04-18 — — CN disclosed
WO-2025070154-A1 POLYAMIDE RESIN, PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT AND METHOD FOR PRODUCING SAME, AND ELECTRONIC COMPONENT 東レ株式会社 2025-04-03 — — WO disclosed
US-4026886-A 7-Acyl-7-arylthiocephalosporins E. R. SQUIBB & SONS, INC. (US) 1977-05-31 — — US disclosed
US-4009208-A N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) STERLING DRUG INC. (US) 1977-02-22 — — US disclosed
US-3965093-A 6-Arylthio penicillanic acid and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1976-06-22 — — US disclosed
US-3960945-A 4-[-(Alkoxy or polyhaloalkoxy)-benzamido]cyclohexanones STERLING DRUG INC. (US) 1976-06-01 — — US disclosed
US-3954744-A ANTIBACTERIAL E. R. SQUIBB & SONS, INC. (US) 1976-05-04 — — US disclosed
US-3954754-A ANTIHYPERTENSIVES SANDOZ LTD. (CH) 1976-05-04 — — US disclosed
US-3952012-A MULTISTAGE MCNEIL LABORATORIES, INCORPORATED (US) 1976-04-20 — — US disclosed
US-3939162-A Anthrapyrimidine dyes BASF AKTIENGESELLSCHAFT (DT) 1976-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022098-A1 BULLEYACONITINE A DERIVATIVE WITH ANALGESIC ACTIVITY, AND PREPARATION METHOD AND APPLICATION THEREOF OPRD1, OPRM1, OPRK1 PARP10 3967/4885NPC1 1009/4885PLK1 4515/4885
US-20250263392-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF IDO2, IDO1, BCR PARP10 687/4885NPC1 2476/4885PLK1 877/4885
US-20250248990-A1 QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE ATP2A1, ATP2A3, ATP2A2 PARP10 3599/4885NPC1 319/4885PLK1 3535/4885
US-12570610-B2 Macromolecule-supported aminobenzazepine compounds BCL6, CLTB, MET PARP10 1465/4885NPC1 2203/4885PLK1 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.