SCHEMBL2764337

SCHEMBL2764337

N[C@H](CC(=O)O)c1ccc(F)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.49
ANPEP P15144 1/20 0.43
KMT2A Q03164 3/20 0.42
CYP2C9 P11712 3/20 0.42
MEN1 O00255 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C19 P33261 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
GABBR2 O75899 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1310948 1.00 FFAR1 (0.49) FFAR1ANPEPKMT2ACYP2C9MEN1
SCHEMBL3338961 1.00 FFAR1 (0.49) FFAR1ANPEPKMT2ACYP2C9MEN1
SCHEMBL7237718 0.94 FFAR1 (0.56) FFAR1
SCHEMBL5360485 0.84 DPP9 (0.43) ANPEPHDAC3HDAC4HDAC1HDAC7
SCHEMBL3554163 0.82 KMT2A (0.46) ANPEPKMT2ACYP2C9MEN1CYP2D6
SCHEMBL7104404 0.82 SMN1; SMN2 (0.54) FFAR1ANPEPKMT2ACYP2C9MEN1
SCHEMBL2765505 0.82 KMT2A (0.46) ANPEPKMT2ACYP2C9MEN1CYP2D6
SCHEMBL284828 0.82 KMT2A (0.46) ANPEPKMT2ACYP2C9MEN1CYP2D6
SCHEMBL2303463 0.82 SMN1; SMN2 (0.54) FFAR1ANPEPKMT2ACYP2C9MEN1
SCHEMBL288753 0.81 GABBR2 (0.59) KMT2ACYP2D6CYP2C19SMN1; SMN2GABBR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202243-A Thermosetting resin composition, cured film, substrate, and electronic component 捷恩智株式会社 2025-06-24 CN disclosed
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
US-20220324865-A1 SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2022-10-13 US disclosed
US-20220119400-A1 QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS ACHILLION PHARMACEUTICALS INC (US) 2022-04-21 US disclosed
US-11248000-B2 Quinazoline and indole compounds to treat medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2022-02-15 US disclosed
EP-3448389-B1 QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS ACHILLION PHARMACEUTICALS INC (US) 2021-09-29 EP disclosed
EP-3305900-B1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION AS (DK) 2021-07-21 EP disclosed
US-10961252-B2 Quinazoline and indole compounds to treat medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2021-03-30 US disclosed
EP-3793559-A1 SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES Bayer Aktiengesellschaft (DE) 2021-03-24 EP disclosed
US-20100285540-A1 Process for the preparation of (R)-Beta-Arylalanines by coupled Racemase/Aminomutase catalysis BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-11-11 US disclosed
US-20100285540-A1 Process for the preparation of (R)-Beta-Arylalanines by coupled Racemase/Aminomutase catalysis BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-11-11 US disclosed
EP-1882740-B1 N-acetyl-(R,S)-B-amino acid acylase gene AJINOMOTO KK (JP) 2010-04-14 EP disclosed
US-20090264300-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2009-10-22 US disclosed
US-20090264300-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2009-10-22 US disclosed
US-20080241895-A1 N-Acetyl-(R,S)-beta-Amino Acid Acylase Gene AJINOMOTO CO., INC. (JP) 2008-10-02 US disclosed
EP-1882740-A1 N-acetyl-(R,S)-B-amino acid acylase gene Ajinomoto Co., Ltd. (JP) 2008-01-30 EP disclosed
WO-2007062664-A2 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2007-06-07 WO disclosed
US-20060178433-A1 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto UBE INDUSTRIES, LTD. (JP) 2006-08-10 US disclosed
EP-1621529-A1 3-AMINO-3-ARYLPROPIONIC ACID n-ALKYL ESTERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-3-ARYLPROPIONIC ACIDS AND ESTERS OF THE ANTIPODES THERETO Ube Industries, Ltd. (JP) 2006-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324865-A1 SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES QDPR, SIRT5, PDXK FFAR1 2061/4885ANPEP 1944/4885KMT2A 3335/4885
US-20090264300-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES RNGTT, DUT, EMG1 FFAR1 4810/4885ANPEP 232/4885KMT2A 1082/4885
US-11248000-B2 Quinazoline and indole compounds to treat medical disorders CFB, TFPI, MAOB FFAR1 4469/4885ANPEP 537/4885KMT2A 4435/4885
US-20220119400-A1 QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS CFB, TFPI, MAOB FFAR1 4469/4885ANPEP 537/4885KMT2A 4435/4885
US-20060178433-A1 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto ALAD, ARSA, ALDH7A1 FFAR1 57/4885ANPEP 148/4885KMT2A 4127/4885
US-10961252-B2 Quinazoline and indole compounds to treat medical disorders CFB, TFPI, MAOB FFAR1 4469/4885ANPEP 537/4885KMT2A 4435/4885
US-20080241895-A1 N-Acetyl-(R,S)-beta-Amino Acid Acylase Gene ACSL4, FASN, BLVRB FFAR1 1173/4885ANPEP 47/4885KMT2A 961/4885
US-20100285540-A1 Process for the preparation of (R)-Beta-Arylalanines by coupled Racemase/Aminomutase catalysis ARSA, RNPEP, DDC FFAR1 1918/4885ANPEP 13/4885KMT2A 1532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.